Diagnosis of allergic rhinitis: inter-rater reliability and predictive value of nasal endoscopic examination: a prospective observational study

Authors

  • E. Eren,

    Corresponding author
    1. Division of Allergy and Immunology, Department of Internal Medicine, Celal Bayar University School of Medicine, Manisa, Turkey
    • Correspondence: E. Eren, Otolaryngology Head and Neck Surgery Clinic, İzmir Katip Çelebi University Atatürk Research and Education Hospital, Otolaryngology Clinic, Karabağlar, Izmir 35360, TurkeyTel.: +902322444444; Fax: +902322431530; e-mail: erd2eren@yahoo.com

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  • A. Aktaş,

    1. Department of Chest Disease, Faculty of Medicine, Celal Bayar University, Manisa, Turkey
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  • S. Arslanoğlu,

    1. Division of Allergy and Immunology, Department of Internal Medicine, Celal Bayar University School of Medicine, Manisa, Turkey
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  • A. Kopar,

    1. Division of Allergy and Immunology, Department of Internal Medicine, Celal Bayar University School of Medicine, Manisa, Turkey
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  • E. Ciğer,

    1. Division of Allergy and Immunology, Department of Internal Medicine, Celal Bayar University School of Medicine, Manisa, Turkey
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  • Y. Özkul,

    1. Division of Allergy and Immunology, Department of Internal Medicine, Celal Bayar University School of Medicine, Manisa, Turkey
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  • K. Önal,

    1. Division of Allergy and Immunology, Department of Internal Medicine, Celal Bayar University School of Medicine, Manisa, Turkey
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  • H. Katılmiş

    1. Division of Allergy and Immunology, Department of Internal Medicine, Celal Bayar University School of Medicine, Manisa, Turkey
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Errata

This article is corrected by:

  1. Errata: Erratum Volume 40, Issue 1, 75, Article first published online: 22 January 2015

Abstract

Objective

To determine the inter-rater reliability of nasal endoscopic findings and the feasibility of diagnosis of allergic rhinitis based solely on symptoms and nasal endoscopy.

Design

Prospective observational study.

Setting

University Teaching hospital.

Participants

One hundred and eight patients were referred from the allergy clinic included in the study.

Main outcome measures

Predictive value of symptoms and nasal endoscopic examination to diagnose allergic rhinitis and inter-rater reliability of the examination were evaluated.

Results

Logistic regression analysis of patient symptoms and nasal examination findings revealed no significant predictive power for any of the symptoms or examination findings. The Fleiss κ coefficient of the three raters was calculated. Inter-rater variability among the three physicians demonstrated that mucosal oedema (κ = 0,48, P < 0.001), polypoid degeneration of the inferior turbinate tail (κ = 0.48, P = 0.01), nasal polyps (κ = 0.96, P < 0.001) and nasal septal deviation (κ = 0.65, P = 0.01) showed significant inter-rater agreement. A low κ coefficient (0.29) was found, and the inter-rater variability among physicians in interpreting the characteristics of nasal secretions was significant (P = 0.04). The inter-rater variability among the three physicians suggested that turbinate hypertrophy (κ = 0.31) and turbinate colour (κ = 0.38) showed no significant inter-rater agreement.

Conclusions

Patient symptoms and nasal endoscopy findings do not provide reliable diagnosis of allergic rhinitis. Turbinate colour and hypertrophy are believed to be related to allergic rhinitis; however, these were subject to marked inter-rater variability in this study.

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