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Successful radiofrequency ablation of an anterior abdominal wall desmoid in familial adenomatous polyposis

Authors

  • E. Barrow,

    Corresponding author
    • Department of General Surgery, University of Manchester and Central Manchester and Manchester Children's University Hospitals NHS Trust, Manchester, UK
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  • K. Newton,

    1. Department of General Surgery, University of Manchester and Central Manchester and Manchester Children's University Hospitals NHS Trust, Manchester, UK
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  • B. Rajashanker,

    1. Department of Radiology, University of Manchester and Central Manchester and Manchester Children's University Hospitals NHS Trust, Manchester, UK
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  • S. Lee,

    1. Department of Radiology, University of Manchester and Central Manchester and Manchester Children's University Hospitals NHS Trust, Manchester, UK
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  • D. G. Evans,

    1. Medical Genetics Research Group and Regional Genetics Service, St Mary's Hospital, University of Manchester and Central Manchester and Manchester Children's University Hospitals NHS Trust, Manchester, UK
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  • J. Hill

    1. Department of General Surgery, University of Manchester and Central Manchester and Manchester Children's University Hospitals NHS Trust, Manchester, UK
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Correspondence to: Miss Emma Barrow, Department of General Surgery, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.

E-mail: emma.barrow@doctors.org.uk

Abstract

Background

Desmoid tumours are an important cause of mortality in familial adenomatous polyposis (FAP). There are few effective treatment strategies. This report describes the use of radiofrequency ablation to debulk and palliate an abdominal wall desmoid tumour in FAP.

Methods

A 22 year old woman with FAP developed a large abdominal wall desmoid tumour after restorative proctocolectomy. The tumour was treated with 16 separate radiofrequency ablations. The follow up was 36 months from the first ablation.

Results

The procedure was well tolerated with minor complications; mild superficial cellulitis and skin ulceration occurred following only one of the ablation sessions. Repeated radiofrequency treatments resulted in a sustained reduction in size and symptoms from the desmoid tumour.

Conclusion

Given the low efficacy of treatments for desmoids in FAP, radiofrequency ablation appears to be a promising modality.

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