Turkish Interstitial Lung Diseases Group
Epidemiology and distribution of interstitial lung diseases in Turkey
Article first published online: 31 JUL 2013
© 2013 John Wiley & Sons Ltd
The Clinical Respiratory Journal
Volume 8, Issue 1, pages 55–62, January 2014
How to Cite
Musellim, B., Okumus, G., Uzaslan, E., Akgün, M., Cetinkaya, E., Turan, O., Akkoclu, A., Hazar, A., Kokturk, N., Calisir, H. C. and Turkish Interstitial Lung Diseases Group (2014), Epidemiology and distribution of interstitial lung diseases in Turkey. The Clinical Respiratory Journal, 8: 55–62. doi: 10.1111/crj.12035
Authorship and contributorship
Benan Musellim, Gul Ongen, Ozlem Ozdemir and Levent Tabak: designed the study.
Gulfer Okumus and Benan Musellim: evaluated patients' and writers' data.
Others: recorded patients' data.
The study protocol was approved by the executive committee of the TTS Clinical Problems Group.
Conflict of interest
None of the authors has a financial relationship with any commercial entity which has an interest in the subject of this manuscript.
- Issue published online: 6 JAN 2014
- Article first published online: 31 JUL 2013
- Accepted manuscript online: 27 MAY 2013 04:21AM EST
- Manuscript Accepted: 20 MAY 2013
- Manuscript Revised: 21 APR 2013
- Manuscript Received: 7 DEC 2012
- distribution ;
- epidemiology ;
- incidence ;
- interstitial lung diseases
There is very few data on the epidemiological features of interstitial lung diseases (ILD) in the literature. These studies on this subject suffer from limited number of patients.
The goal of this study was to evaluate the epidemiological features of ILD in Turkey.
Fifty-four investigators, 31 centres in 19 cities from six regions of Turkey, participated in the study. Two thousand two hundred forty-five newly diagnosed patients (51.8% females), led by Turkish Thoracic Society Clinical Problems Study Group, enrolled in this prospective study.
The mean age was 51.8 ± 16.7 years. The mean age among males was 50.5 ± 18.6 years and 53.0 ± 14.6 years among females (P < 0.001). 23.8% of the cases had ILD with known causes, while 39.4% were in granulomatous group, 23.7% were idiopathic, and 4.4% were in the unclassified group. Overall, histopathologically confirmed diagnosis rate was 40.4%. Sarcoidosis was the most common disease (37%), whereas cases with idiopathic pulmonary fibrosis (IPF) constituted 19,9% of patients. 53% of the sarcoidosis patients were females, and the ratio reaches to 75% under 50 years of age (for this group, IPF ratio is %3). In contrast, sarcoidosis and IPF ratios were equal in males (25%). Sarcoidosis was 8% in men over 50, while IPF was %45.
The overall incidence of ILD in Turkey was computed to be 25.8/100 000.