SEARCH

SEARCH BY CITATION

Keywords:

  • adults ;
  • references ;
  • Saudi Arabia ;
  • spirometry

Abstract

Objectives

To derive prediction equations of spirometric values of healthy Saudi adults and to compare the derived equations with equations reported in selected population.

Methods

Cross-sectional study of healthy nonsmoking men and women Saudi adults. The measured spirometric values were the forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), peak expiratory flow (PEF) and forced mid-expiratory flow (FEF 25%–75%).

Results

A total of 621 spirometric tests were done. The prediction equations were derived using the following formula: Predicted spirometric value = constant + (b1 × age) + (b2 × height (cm)), where b1 and b2 represent the regression coefficients for age and height, respectively.

VariableConstantAge (years)Height (cm)VariableConstantAge (years)Height (cm)
Males (n = 292)   Females (n = 175)   
FVC−2.933−0.0180.046FVC−3.470−0.0160.045
FEV1−1.886−0.0190.036FEV1−2.482−0.0180.036
FEV1/FVC (%)98.41−0.095−0.068FEV1/FVC (%)100.67−0.142−0.072
PEF17.274−1.2433.471PEF−226.648−0.4994.076
FEF25%–75%0.100−0.0240.027FEF25%−75%−1.337−0.0210.031

The means of the measured FVC and FEV1 were significantly lower than the predicted values derived by the American equations of −7.2% and −4.6% among males, respectively (P value < 0.00001), and −4.7%, and −5.26% among females, respectively (P value < 0.00001).

Conclusion

The reference spirometric values derived in our study were significantly lower than the predicted values derived by the American equations.