Authorship and contributorship
Learning curve of conventional transbronchial needle aspiration
Version of Record online: 1 OCT 2013
© 2013 John Wiley & Sons Ltd
The Clinical Respiratory Journal
Volume 8, Issue 1, pages 79–85, January 2014
How to Cite
Tutar, N., Büyükoğlan, H., Yılmaz, İ., Kanbay, A., Önal, Ö., Bilgin, M., Canöz, Ö., Demir, R., Oyak, F. S., Gülmez, İ. and Çetinkaya, E. (2014), Learning curve of conventional transbronchial needle aspiration. The Clinical Respiratory Journal, 8: 79–85. doi: 10.1111/crj.12041
Nuri Tutar: collected and analyzed the data, undertook the statistical analysis, and wrote the initial and final drafts of the manuscript. Hakan Büyükoglan: helped to collect the data, undertook the statistical analysis, and wrote the final drafts of the manuscript. İnsu Yılmaz: helped to collecet the data. Asiye Kanbay: helped to collect the data and reviewed the manuscript. Omer Onal: helped to collected the surgical data. Mehmet Bilgin: helped to collected the surgical data. Ozlem Canoz: helped to collected the pathological data. Ramazan Demir: conceived of the study, helped to collect the data and reviewed the manuscript. F. Sema Oymak: helped to collect the data and reviewed the manuscript. Inci Gülmez: helped to collect the data and reviewed the manuscript. Erdogan Cetinkaya: conceived of the study and reviewed the manuscript.
The protocol has been approved by the Audit and Research Ethics Committee of the Erciyes University and was performed with the ethical standards laid down in the 2000 Declaration of Helsinki.
Conflict of interest
The authors have stated explicitly that there are no conflicts of interest in connection with this article.
- Issue online: 6 JAN 2014
- Version of Record online: 1 OCT 2013
- Accepted manuscript online: 15 JUL 2013 03:06AM EST
- Manuscript Accepted: 9 JUL 2013
- Manuscript Revised: 12 JUN 2013
- Manuscript Received: 15 APR 2013
- learning curve;
- mediastinal lymphadenopathy;
- transbronchial aspiration
Background and Aims
Intrathoracic lymphadenopathy usually occurs as a result of neoplasm, granulomatous diseases, infections or reactive hyperplasia. Conventional transbronchial needle aspiration (C-TBNA) is a cheap and safe procedure for diagnosing intrathoracic lymphadenopathy. The aim of this study was to assess the learning curve and diagnostic accuracy of C-TBNA after an observational education programme.
In the present study, we retrospectively evaluated our first 62 C-TBNA procedures at Erciyes University between May 2012 and December 2012 after an observational education programme. The first 31 patients were defined as group A, and the second 31 patients as group B.
One hundred and seven lymph nodes were sampled in 62 patients by C-TBNA. Adequate lymph node samples were obtained in 52 of the 62 patients (83.8%). In these 52 patients, two patients had a diagnosis of ‘suspicious of malignancy’ by C-TBNA, and these patients were excluded from the analysis. In the remaining 50 cases who had adequate results, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy per patient were 80.6%, 92.9%, 96.7%, 65.0% and 84.0%, respectively. The diagnostic accuracy rates of C-TBNA for Group A and B were 72.0% (18/25) and 96.0% (24/25), and the difference was statistically significant (P < 0.05).
C-TBNA is a useful diagnostic procedure for sampling intrathoracic lymphadenopathies and masses that are adjacent to the bronchial system. An observational education programme is helpful for learning C-TBNA. The diagnostic yield improves in time, and approximately 30 procedures may be sufficient to achieve successful results.