Conflicts of interest: No conflict of interest declared.
Multiorgan transplantation from a deceased donor with intravascular diffuse large B-cell lymphoma: transmission of the disease and results of treatment
Article first published online: 19 AUG 2014
© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Volume 28, Issue 10, pages 1080–1083, October 2014
How to Cite
Multiorgan transplantation from a deceased donor with intravascular diffuse large B-cell lymphoma: transmission of the disease and results of treatment., , , .
- Issue published online: 18 OCT 2014
- Article first published online: 19 AUG 2014
- Accepted manuscript online: 8 JUL 2014 08:34PM EST
- Manuscript Accepted: 6 JUL 2014
- diffuse large B-cell lymphoma;
- kidney transplantation;
- liver transplantation;
- transplant complications
This report presents the transplantation of two kidneys and the liver from a deceased donor with suspected autoimmune encephalomeningitis (ADEM). Due to an atypical post-transplantation clinical course, the transplanted kidneys were biopsied and this disclosed diffuse large B-cell (DLBC) lymphoma of the intravascular type in each kidney. The same malignancy was found in the postmortem donor brain examination. The renal allografts from the two recipients were removed: despite every effort, one patient died, while chemotherapy was successful in the second. No malignancy was observed in the liver transplant recipient, who received prophylactic chemotherapy. These cases highlight the occasional failure of organ donor disease screening and the consequent unforeseen complications.