• 1
    Telen MJ. Erythrocyte adhesion receptors: blood group antigens and related molecules. Transfus Med Rev . 2005; 19: 3244.
  • 2
    Zennadi R, Moeller BJ, Whalen EJ, Batchvarova M, Xu K, Shan S, Delahunty M, Dewhirst MW, Telen MJ. Epinephrine-induced activation of LW-mediated sickle cell adhesion and vaso-occlusion in vivo. Blood. 2007; 110: 27082717.
  • 3
    Hines PC, Zen Q, Burney SN, Shea DA, Ataga KI, Orringer EP, Telen MJ, Parise LV. Novel epinephrine and cyclic AMP-mediated activation of BCAM/Lu-dependent sickle (SS) RBC adhesion. Blood . 2003; 101: 32813287.
  • 4
    Zennadi R, Hines PC, De Castro LM, Cartron J-P, Parise LV, Telen MJ. Epinephrine acts through erythroid signaling pathways to activate sickle cell adhesion to endothelium via LW-{alpha}v{beta}3 interactions. Blood . 2004; 104: 37743781.
  • 5
    Zennadi R, Chien A, Xu K, Batchvarova M, Telen MJ. Sickle red cells induce adhesion of lymphocytes and monocytes to endothelium. Blood . 2008; 112: 34743483.
  • 6
    Shiu YT, Udden MM, McIntire LV. Perfusion with sickle erythrocytes up-regulates ICAM-1 and VCAM-1 gene expression in cultured human endothelial cells. Blood. 2000; 95: 32323241.
  • 7
    Natarajan M, Udden MM, McIntire LV. Adhesion of sickle red blood cells and damage to interleukin-1 beta stimulated endothelial cells under flow in vitro. Blood . 1996; 87: 48454852.
  • 8
    Okpala I. The intriguing contribution of white blood cells to sickle cell disease—a red cell disorder. Blood Rev . 2004; 18: 6573.
  • 9
    Sultana C, Shen Y, Rattan V, Johnson C, Kalra VK. Interaction of sickle erythrocytes with endothelial cells in the presence of endothelial cell conditioned medium induces oxidant stress leading to transendothelial migration of monocytes. Blood . 1998; 92: 39243935.
  • 10
    Unthank JL, Lash JM, Nixon JC, Sidner RA, Bohlen HG. Evaluation of carbocyanine-labeled erythrocytes for microvascular measurements. Microvasc Res . 1993; 45: 193210.
  • 11
    Dewhirst MW, Tso CY, Oliver R, Gustafson CS, Secomb TW, Gross JF. Morphologic and hemodynamic comparison of tumor and healing normal tissue microvasculature. Int J Radiat Oncol Biol Physiol . 1989; 17: 9199.
  • 12
    Hebbel RP, Yamada O, Moldow CF, Jacob HS, White JG, Eaton JW. Abnormal adherence of sickle erythrocytes to cultured vascular endothelium: possible mechanism for microvascular occlusion in sickle cell disease. J Clin Invest . 1980; 65: 154160.
  • 13
    Hebbel RP, Moldow CF, Steinberg MH. Modulation of erythrocyte–endothelial interactions and the vasocclusive severity of sickling disorders. Blood . 1981; 58: 947952.
  • 14
    Sager G. Receptor binding sites for beta-adrenergic ligands on human erythrocytes. Biochem Pharmacol . 1982; 31: 99104.
  • 15
    Sager G, Jacobsen S. Effect of plasma on human erythrocyte beta-adrenergic receptors. Biochem Pharmacol. 1985; 34: 37673771.
  • 16
    Hebbel RP, Boogaerts MA, Koresawa S, Jacob HS, Eaton JW, Steinberg MH. Erythrocyte ­adherence to endothelium as a determinant of vasocclusive severity in sickle cell disease. Trans Assoc Am Phys . 1980; 93: 9499.
  • 17
    Zen Q, Batchvarova M, Twyman CA, Eyler CE, Qiu H, De Castro LM, Telen MJ. B-CAM/LU expression and the role of B-CAM/LU activation in binding of low- and high-density red cells to laminin in sickle cell disease. Am J Hematol . 2004; 75: 6372.
  • 18
    Pegelow CH, Colangelo L, Steinberg M, Wright EC, Smith J, Phillips G, Vichinsky E. Natural history of blood pressure in sickle cell disease: risks for stroke and death associated with relative hypertension in sickle cell anemia. Am J Med. 1997; 102: 171177.
  • 19
    Fitzhugh CD, Lauder N, Jonassaint JC, Telen MJ, Zhao X, Wright EC, Gilliam FR, De Castro LM. Cardiopulmonary complications leading to premature deaths in adult patients with sickle cell disease. Am J Hematol . 2010; 85: 3640.
  • 20
    Vij R, Machado RF. Pulmonary complications of hemoglobinopathies. Chest . 2010; 138:973983.
  • 21
    Murphy MM, Zayed MA, Evans A, Parker CE, Ataga KI, Telen MJ, Parise LV. Role of Rap1 in promoting sickle red blood cell adhesion to laminin via BCAM/LU. Blood . 2005; 105: 33223329.
  • 22
    Gauthier E, Rahuel C, Wautier MP, El Nemer W, Gane P, Wautier JL, Cartron JP, Colin Y, Le Van Kim C. Protein kinase A-dependent phosphorylation of Lutheran/basal cell adhesion molecule glycoprotein regulates cell adhesion to laminin alpha5. J Biol Chem . 2005; 280: 3005530062.
  • 23
    Eyler CE, Jackson T, Elliott LE, De Castro LM, Jonassaint J, Ashley-Koch A, Telen MJ. Beta(2)-Adrenergic receptor and adenylate cyclase gene polymorphisms affect sickle red cell adhesion. Br J Haematol. 2008; 141: 105108.
  • 24
    Hoppe C, Klitz W, Cheng S, Apple R, Steiner L, Robles L, Girard T, Vichinsky E, Styles L. Gene interactions and stroke risk in children with sickle cell anemia. Blood . 2004; 103: 23912396.
  • 25
    Büscher R, Herrmann V, Insel PA. Human adrenoceptor polymorphisms: evolving recognition of clinical importance. Trends Pharmacol Sci . 1999; 20: 9499.
  • 26
    Garland E, Biaggioni I. Genetic polymorphisms of adrenergic receptors. Clin Auton Res. 2001; 11: 6778.