Myoepithelial carcinoma of the retromolar area with extensive mandibular involvement
Article first published online: 25 SEP 2012
Copyright © 2012 John Wiley & Sons A/S
Journal of Cutaneous Pathology
Volume 39, Issue 12, pages 1135–1143, December 2012
How to Cite
Myoepithelial carcinoma of the retromolar area with extensive mandibular involvement., , , , , .
- Issue published online: 26 NOV 2012
- Article first published online: 25 SEP 2012
- Manuscript Accepted: 7 APR 2012
- Manuscript Revised: 19 FEB 2012
- Manuscript Received: 30 DEC 2011
- myoepithelial carcinoma;
- oral cavity;
- salivary gland tumor
Myoepithelial tumors were first described in 1943, and account for less than 1% of all salivary gland neoplasms. Their malignant variant, myoepithelial carcinoma, was first reported by Stromeyer et al. in 1975 and represents a very rare entity, characterized by distinct morphologic heterogeneity and an infiltrative growth pattern into adjacent tissues. However, there have been few reports on myoepithelial carcinoma affecting intra-oral minor salivary glands, and its immunohistochemical features have been poorly illustrated. We herein describe a rare case of myoepithelial carcinoma affecting the retromolar region of a 52-year-old woman that caused extensive mandibular bone destruction. We also reviewed the English literature concerning the involvement of intra-oral minor salivary glands by myoepithelial carcinoma.