Spindle-cell variant of primary cutaneous follicle center lymphoma spreading to the hepatobiliary tree, mimicking Klatskin tumor
Article first published online: 20 NOV 2012
Copyright © 2012 John Wiley & Sons A/S
Journal of Cutaneous Pathology
Volume 40, Issue 1, pages 56–60, January 2013
How to Cite
Spindle-cell variant of primary cutaneous follicle center lymphoma spreading to the hepatobiliary tree, mimicking Klatskin tumor., , , , , , .
- Issue published online: 21 DEC 2012
- Article first published online: 20 NOV 2012
- Manuscript Accepted: 3 JUN 2012
- Manuscript Revised: 16 MAY 2012
- Manuscript Received: 21 OCT 2011
- cutaneous B-cell lymphoma;
- cutaneous spindle-cell lymphoma;
- hilar cholangiocarcinoma;
- Klatskin mimicking tumor
Primary cutaneous follicle center lymphoma (pcFCL) is an indolent type of primary cutaneous B-cell lymphoma (pcBCL) rarely disseminating to other organs. PcBCL with spindle-cell morphology has been described as a rare variant of pcFCL but the prognosis data of this variant is sparse.
We report a rare case of spindle-cell pcFCL with CD20+, CD79a+, CD3+, Bcl-6+, Mum-1− and CD10−tumor cells that infiltrated the hepatic hilum, mimicking a Klatskin tumor.
On the basis of the sparse published data on spindle-cell morphology of pcBCL, this growth pattern should elicit awareness of an increased risk of systemic involvement in the otherwise indolent pcFCL.