Borderline sebaceous neoplasm in a renal transplant patient without Muir-Torre syndrome
Version of Record online: 23 NOV 2012
© 2012 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd
Journal of Cutaneous Pathology
Volume 40, Issue 3, pages 336–340, March 2013
How to Cite
Borderline sebaceous neoplasm in a renal transplant patient without Muir-Torre syndrome., , , .
- Issue online: 20 FEB 2013
- Version of Record online: 23 NOV 2012
- Manuscript Accepted: 6 SEP 2012
- Manuscript Revised: 26 MAY 2012
- Manuscript Received: 6 APR 2012
- adnexal neoplasm;
- DNA repair;
Borderline sebaceous neoplasms are rare tumors that can be challenging to diagnose because of their admixture of histopathologic features. Most such tumors have been described in patients with Muir-Torre syndrome (MTS). We report the case of an immunosuppressed, 82-year-old African-American woman without MTS who developed a rapidly growing lesion on the left cheek. Histopathology revealed a borderline sebaceous neoplasm with predominant features of sebaceous adenoma and with focal features raising concern for the possibility of an evolving, well-differentiated, low-grade sebaceous carcinoma with a high mitotic index. In the setting of immunosuppression, borderline sebaceous neoplasms may occur outside of MTS; careful evaluation and conservative treatment are recommended in managing such tumors.