Lymphoplasmacytic plaque in children: a report of two new cases with review of the literature
Article first published online: 20 NOV 2012
Copyright © 2012 John Wiley & Sons A/S
Journal of Cutaneous Pathology
Volume 40, Issue 1, pages 50–55, January 2013
How to Cite
Lymphoplasmacytic plaque in children: a report of two new cases with review of the literature., , , , , .
- Issue published online: 21 DEC 2012
- Article first published online: 20 NOV 2012
- Accepted manuscript online: 18 OCT 2012 07:39AM EST
- Manuscript Accepted: 19 AUG 2012
- Manuscript Revised: 31 JUL 2012
- Manuscript Received: 5 JUN 2012
Lymphoplasmacytic plaque in children has been proposed as a rare, emerging clinicopathologic entity characterized by solitary, extratruncal, asymptomatic papules and plaques that are typically found in healthy young Caucasian females. Biopsy of these lesions reveals a dermal lymphoplasmacytic infiltrate with or without epithelioid granulomas. Two unique patients with lymphoplasmacytic plaque in children are presented in this report, including a 26-month-old female with a lesion on her finger, who represents both the youngest described patient and the first documented with a finger lesion, as well as a 17-year-old young woman with a left thigh lesion, who represents the patient with the longest clinically and histopathologically observed lesion to date. These two additional patients corroborate the experience of lymphoplasmacytic plaque in children in the six previously reported cases and further expand the clinicopathologic spectrum of the disease. Recognition of lymphoplasmacytic plaque in children is important to facilitate distinction from potential differential considerations, including lymphoproliferative disorders and infectious conditions, particularly as the experience to date appears to suggest that lymphoplasmacytic plaque in children represent a reactive (pseudolymphomatous) condition.