Congenital disseminated tufted angioma
Article first published online: 4 FEB 2013
© 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd
Journal of Cutaneous Pathology
Volume 40, Issue 4, pages 405–408, April 2013
How to Cite
Congenital disseminated tufted angioma., , , .
- Issue published online: 19 MAR 2013
- Article first published online: 4 FEB 2013
- Manuscript Accepted: 10 NOV 2012
- Manuscript Revised: 19 OCT 2012
- Manuscript Received: 13 JUL 2012
- tufted angioma
Tufted angioma represents a rare vascular tumor that can develop in children and young adults. It usually presents as solitary plaque or large tumor on the extremities, trunk or other anatomic sites. Histopathologically, it is characterized by proliferation of closely packed capillaries in the dermis in a ‘cannonball’ distribution. We described a 2-month-old child who developed widespread disseminated red papules since her birth. Eight lesions were excised for histopathology, seven of which showed typical cannonball-like distribution of proliferative capillaries, characteristic of tufted angioma, and one on the hand which showed focal disseminated proliferation of endothelial cells. Immunohistochemistry showed focal D2-40 positivity in one lesion and was negative in the other seven. Expression of Prox1 and Glut-1 was negative in all lesions. This case represented a disseminated form of tufted angioma.