Neutrophilic panniculitis developing after treatment of metastatic melanoma with vemurafenib


Gene H. Kim, MD

1500 San Pablo Street, Los Angeles, CA 90033, USA

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Vemurafenib is an inhibitor of BRAF and is used to treat patients with metastatic melanoma who carry a V600E BRAF mutation. Recently, four patients have been described in the literature who developed a neutrophilic panniculitis following treatment with a BRAF inhibitor. We present an additional case and review the clinical findings of the cases reported to date.