Nevoid follicular mucinosis: a new type of hair follicle nevus

Authors

  • Gianluca Tadini,

    Corresponding author
    1. Pediatric Clinic 1, Fondazione IRCCS Cà Granda—Ospedale Maggiore Policlinico di Milano, University of Milan, Milan, Italy
    • Section of Dermatology, Fondazione IRCCS Cà Granda—Ospedale Maggiore Policlinico di Milano, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
    Search for more papers by this author
  • Maria P. Boldrini,

    1. Pediatric Dermatology Division, Hospital General de Agudos, JM Ramos Mejía, Buenos Aires, Argentina
    Search for more papers by this author
  • Michela Brena,

    1. Section of Dermatology, Fondazione IRCCS Cà Granda—Ospedale Maggiore Policlinico di Milano, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
    Search for more papers by this author
  • Lidia Pezzani,

    1. Section of Dermatology, Fondazione IRCCS Cà Granda—Ospedale Maggiore Policlinico di Milano, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
    Search for more papers by this author
  • Lorenzo Marchesi,

    1. Department of Dermatology, Ospedali Riuniti di Bergamo, Bergamo, Italy
    Search for more papers by this author
  • Franco Rongioletti

    1. Section of Dermatology, DISSAL and Institute of Pathology, University of Genoa, Genoa, Italy
    Search for more papers by this author

Gianluca Tadini

Via Pace 9, Milan, Italy

Tel: +390255035326

Fax: +390255035118

e-mail: gtadinicmce@unimi.it

Abstract

Follicular mucinosis represents a term for a histopathologic reaction pattern in follicular epithelium. It is a characteristic of alopecia mucinosa. However, it may also occur in a variety of unrelated conditions. Epidermal nevi are considered to be hamartomatous disorders and they can show a predominant component of non-organoid (keratinocytes) and/or organoid nevi. All the cases of epidermal nevi described with mucin deposits until now are reported as mucinous nevus or mucinous eccrine nevus; in the first type of disorder, diffuse mucin deposition is only seen in the papillary dermis, and in the second type, the mucin is found around the proliferation of eccrine structures. We believe this is the first reported case of epidermal nevus along Blaschko's lines exhibiting typical microscopic findings of mucinosis exclusively distributed inside the follicular epithelia.

Ancillary