Combined cutaneous smooth muscle hamartoma and nevus flammeus


  • Angel Fernandez-Flores,

    Corresponding author
    1. Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain,
    • Angel Fernandez-Flores, MD, PhD

      Servicio de Anatomía Patologica, Hospital El Bierzo, Medicos sin Fronteras 7, Ponferrada 24411, Spain

      Tel: +34 987 45 42 00

      Fax: (0034) 987412540


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  • Marcela Saeb-Lima

    1. Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, INER/CIENI, Hospital Angeles Lomas, Mexico City, México
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We report on a combined cutaneous smooth muscle hamartoma and reticulate port-wine stain on the thigh of a 26-year-old woman. The lesion measured 30 cm in longest diameter and presented clinically with a macular erythematous telangiectatic vascular appearance. It was focally ulcerated, which represented the patient's main complaint. Histopathological study demonstrated smooth muscle bundles closely intermingled with a vascular component comprised of capillaries and venules. Such a morphological presentation is, to the best of our knowledge, unique in the literature.