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Keywords:

  • allograft;
  • eyelid;
  • foreign body giant cell reaction;
  • rejection;
  • xenograft

Objective

A foreign body giant cell (FBGC) reaction may occur in response to implanted xenogenic biomaterials. Here we report a FBGC reaction to the recently introduced xenogenic biomaterial, tarSys™, used for correction of lower eyelid retraction.

Method

A retrospective chart review of two patients with FBGC reaction to tarSys™ implantation was performed.

Results

Two patients (aged 51, 58 year) with lower eyelid retraction underwent surgical implantation of tarSys™ spacer grafts for correction. Both patients subsequently experienced chronic swelling requiring graft removal. Examination of the specimens showed a palisading FBGC reaction around acellular pink fibrillar material.

Conclusion

A FBGC reaction may follow implantation of the tarSys™ xenograft.