By creating new media channels that enable anyone to reach the public directly, the Internet has reduced the need for a middleman, resulting in the “disintermediation” of science communication. New providers of informal science learning are emerging in community settings, as well as in sources online. These changes raise the critical question of how science centers can adapt to an expanding ecosystem of mediated and unmediated sources. This article points out strengths of science centers that offer some grounds for optimism. Promising efforts are identified and possible directions are proposed at the community and institutional level.