Conflict of interest Rebecca Körner has a scholarship in dermatopathology from the “Deutsche Dermatologische Gesellschaft” (DDG).
Histopathology of body art revisited – analysis and discussion of 19 cases
Article first published online: 29 AUG 2013
© The Authors | Journal compilation © Blackwell Verlag GmbH, Berlin
JDDG: Journal der Deutschen Dermatologischen Gesellschaft
Volume 11, Issue 11, pages 1073–1080, November 2013
How to Cite
Körner, R., Pföhler, C., Vogt, T. and Müller, C. S. L. (2013), Histopathology of body art revisited – analysis and discussion of 19 cases. JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 11: 1073–1080. doi: 10.1111/ddg.12178
- Issue published online: 14 OCT 2013
- Article first published online: 29 AUG 2013
- Manuscript Accepted: 20 JUN 2013
- Manuscript Received: 3 APR 2013
Background and Objectives
With the number of tattoos increasing, a rising number of complications have also been reported, such as allergic and foreign body reactions or the development of malignant tumors. We discuss 19 patients with alterations in skin tattoos, define clinicopathologic characteristics and give a brief review of the literature.
Patients and Methods
Biopsy specimens were obtained in 13 of 19 patients. In all cases, staining was performed with hematoxylin-eosin, periodic acid-Schiff, CD68, CD123, and CD163. The inflammatory infiltrate was classified according to the pattern analysis of Ackerman.
Three of 19 patients (15.8%) had temporary tattoos with henna and 16 (84.2%) had permanent tattoos. Histologically, among the 13 biopsy specimens we found signs of acute contact dermatitis in 2 (15.3%), lupus-like patterns in 2 (15.3%), foreign body dermatitis in 5 (38.4%), deposition of pigment without inflammation or simple scarring in 2 (15.3%), and tumors in 2 patients (15.2%), 1 of which was a malignant melanoma.
Clinical presentation frequently, but not always, correlates with the histologic pattern. Obtaining a biopsy can be helpful in determining further investigations, for example allergy testing or a search for systemic involvement in cases of tattoo sarcoidosis.