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desc12092-sup-0003-TableS1.docxWord document86KTable S1 Summary of imaging results from whole-brain analyses. All results exceed a p-value/cluster size combination (p < .01/45 voxels) that corresponds to whole-brain p < .05, corrected for multiple comparisons as calculated with Monte Carlo simulations in AFNI (3dClustSim), except for the main effect of difficulty, where a p-value/cluster size combination of p < .0005/10 voxels is used to distinguish subclusters within larger functional activations (>1000 voxels).
desc12092-sup-0001-FigS1.tiffimage/tif2410KFig S1 Main effect of difficulty. Brain regions showing differential activity as a function of difficulty (hard > easy). Activations, thresholded at p < .05, whole brain corrected, are rendered on a representative high-resolution anatomical scan. Slices were selected (z = −30, −10, 0, 10, 20, 30) to highlight the basal ganglia thalamocortical circuit.
desc12092-sup-0002-FigS2.tiffimage/tif1094KFig S2 Age by reward interaction in brain and behavior. Top: Behavioral plot of difference score between large and small reward trials across early-adolescents (11–15), late-adolescents (16–20) and adults (21 and up); average z-transformed reaction times. Middle: BOLD activity in dlPFC as a function of large reward bias and age group. Bottom: BOLD activity in IPS as a function of reward bias and age group. dlPFC = dorsolateral prefrontal cortex; IPS = intraparietal sulcus

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