Reporter Mouse Lines for Fluorescence Imaging

Authors

  • Takaya Abe,

    1. Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Developmental Biology (CDB), Kobe, Hyogo, Japan
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  • Toshihiko Fujimori

    Corresponding author
    1. Division of Embryology, National Institute for Basic Biology (NIBB), Okazaki, Aichi, Japan
    • Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Developmental Biology (CDB), Kobe, Hyogo, Japan
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Author to whom all correspondence should be addressed.

Email: fujimori@nibb.ac.jp

Abstract

The use of live imaging approaches to examine and understand the dynamic processes that take place during mouse development has become widespread. Several groups have reported their success in generating different reporter mouse lines that express a variety of fluorescent markers for imaging. However, there is currently no established database of the reporter mouse lines available for live imaging, such as the Cre transgenic lines (Cre-X-Mice). Researchers therefore often have difficulties in determining which reporter mouse line meets their research purposes. In this review, we summarize some of the reporter mouse lines that have been generated for live imaging studies, and discuss their characteristics.

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