SEARCH

SEARCH BY CITATION

References

  • Ajioka, I., Martins, R. A., Bayazitov, I. T., Donovan, S., Johnson, D. A., Frase, S., Cicero, S. A., Boyd, K., Zakharenko, S. S. & Dyer, M. A. 2007. Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice. Cell 131, 378390.
  • Andrusiak, M. G., McClellan, K. A., Dugal-Tessier, D., Julian, L. M., Rodrigues, S. P., Park, D. S., Kennedy, T. E. & Slack, R. S. 2011. Rb/E2F regulates expression of neogenin during neuronal migration. Mol. Cell. Biol. 31, 238247.
  • Andrusiak, M. G., Vandenbosch, R., Park, D. S. & Slack, R. S. 2012. The retinoblastoma protein is essential for survival of postmitotic neurons. J. Neurosci. 32, 1480914814.
  • Angevine, J. B. Jr & Sidman, R. L. 1961. Autoradiographic study of cell migration during histogenesis of cerebral cortex in the mouse. Nature 192, 766768.
  • Besson, A., Hwang, H. C., Cicero, S., Donovan, S.L., Gurian-West, M., Johnson, D., Clurman, B.E., Dyer, M.A. & Roberts, J.M. 2007. Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype. Genes Dev. 21, 17311746.
  • Binne, U. K., Classon, M. K., Dick, F. A., Wei, W., Rape, M., Kaelin, W. G., . Jr, Naar & A. M. Dyson, N. J. 2007. Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit. Nat. Cell Biol. 9, 225232.
  • Buchkovich, K., Duffy, L. A. & Harlow, E. 1989. The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell 58, 10971105.
  • Burkhart, D. L. & Sage, J. 2008. Cellular mechanisms of tumour suppression by the retinoblastoma gene. Nat. Rev. Cancer 8, 671682.
  • Cajal, R. Y. 1909–1911. Histologie dù Système Nerveux de l′homme et des vertébrés. Maloine, París.
  • Camarda, G., Siepi, F., Pajalunga, D., Bernardini, C., Rossi, R., Montecucco, A., Meccia, E. & Crescenzi, M. 2004. A pRb-independent mechanism preserves the postmitotic state in terminally differentiated skeletal muscle cells. J. Cell Biol. 167, 417423.
  • Chellappan, S. P., Hiebert, S., Mudryj, M., Horowitz, J. M. & Nevins, J. R. 1991. The E2F transcription factor is a cellular target for the RB protein. Cell 65, 10531061.
  • Chen, D., Livne-Bar, I., Vanderluit, J. L., Slack, R. S., Agochiya, M. & Bremner, R. 2004. Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma. Cancer Cell 5, 539551.
  • Chen, D., Opavsky, R., Pacal, M., Tanimoto, N., Wenzel, P., Seeliger, M. W., Leone, G. & Bremner, R. 2007. Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a. PLoS Biol. 5, e179.
  • Chen, P. L., Scully, P., Shew, J. Y., Wang, J. Y. & Lee, W. H. 1989. Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell 58, 11931198.
  • Chicas, A., Wang, X., Zhang, C., Mccurrach, M., Zhao, Z., Mert, O., Dickins, R. A., Narita, M., Zhang, M. & Lowe, S. W. 2010. Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence. Cancer Cell 17, 376387.
  • Cobrinik, D., Whyte, P., Peeper, D. S., Jacks, T. & Weinberg, R. A. 1993. Cell cycle-specific association of E2F with the p130 E1A-binding protein. Genes Dev. 7, 23922404.
  • Cunningham, J. J., Levine, E. M., Zindy, F., Goloubeva, O., Roussel, M. F. & Smeyne, R. J. 2002. The cyclin-dependent kinase inhibitors p19(Ink4d) and p27(Kip1) are coexpressed in select retinal cells and act cooperatively to control cell cycle exit. Mol. Cell. Neurosci. 19, 359374.
  • d'Adda di Fagagna, F., Reaper, P. M., Clay-Farrace, L., Fiegler, H., Carr, P., Von Zglinicki, T., Saretzki, G., Carter, N. P. & Jackson, S. P. 2003. A DNA damage checkpoint response in telomere-initiated senescence. Nature 426, 194198.
  • Dannenberg, J. H., Van Rossum, A., Schuijff, L. & Te Riele, H. 2000. Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions. Genes Dev. 14, 30513064.
  • DeCaprio, J. A., Ludlow, J. W., Lynch, D., Furukawa, Y., Griffin, J., Piwnica-Worms, H., Huang, C. M. & Livingston, D. M. 1989. The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell 58, 10851095.
  • Dehay, C. & Kennedy, H. 2007. Cell-cycle control and cortical development. Nat. Rev. Neurosci. 8, 438450.
  • Devoto, S. H., Mudryj, M., Pines, J., Hunter, T. & Nevins, J. R. 1992. A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex. Cell 68, 167176.
  • Dimri, G. P., Lee, X., Basile, G., Acosta, M., Scott, G., Roskelley, C., Medrano, E. E., Linskens, M., Rubelj, I. & Pereira-Smith, O. 1995. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl Acad. Sci. USA 92, 93639367.
  • Donovan, S. L., Schweers, B., Martins, R., Johnson, D. & Dyer, M. A. 2006. Compensation by tumor suppressor genes during retinal development in mice and humans. BMC Biol. 4, 14.
  • Dyer, M. A., Martins, R., Da Silva Filho, M., Muniz, J. A., Silveira, L. C., Cepko, C. L. & Finlay, B. L. 2009. Developmental sources of conservation and variation in the evolution of the primate eye. Proc. Natl Acad. Sci. USA 106, 89638968.
  • Ferguson, K. L., McClellan, K. A., Vanderluit, J. L., Mcintosh, W. C., Schuurmans, C., Polleux, F. & Slack, R. S. 2005. A cell-autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration. EMBO J. 24, 43814391.
  • Finlay, B. L., Hersman, M. N. & Darlington, R. B. 1998. Patterns of vertebrate neurogenesis and the paths of vertebrate evolution. Brain Behav. Evol. 52, 232242.
  • Frank, C. L. & Tsai, L. H. 2009. Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity. Neuron 62, 312326.
  • Friend, S. H., Bernards, R., Rogelj, S., Weinberg, R. A., Rapaport, J. M., Albert, D. M. & Dryja, T. P. 1986. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323, 643646.
  • Ge, W. P., Miyawaki, A., Gage, F. H., Jan, Y. N. & Jan, L. Y. 2012. Local generation of glia is a major astrocyte source in postnatal cortex. Nature 484, 376380.
  • Gong, S., Zheng, C., Doughty, M. L., Losos, K., Didkovsky, N., Schambra, U. B., Nowak, N. J., Joyner, A., Leblanc, G., Hatten, M. E. & Heintz, N. 2003. A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature 425, 917925.
  • Gonzalo, S., Garcia-Cao, M., Fraga, M. F., Schotta, G., Peters, A. H., Cotter, S. E., Eguia, R., Dean, D. C., Esteller, M., Jenuwein, T. & Blasco, M. A. 2005. Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin. Nat. Cell Biol. 7, 420428.
  • Goto, T., Mitsuhashi, T. & Takahashi, T. 2004. Altered patterns of neuron production in the p27 knockout mouse. Dev. Neurosci. 26, 208217.
  • Gu, W., Schneider, J. W., Condorelli, G., Kaushal, S., Mahdavi, V. & Nadal-Ginard, B. 1993. Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 72, 309324.
  • Guo, K., Wang, J., Andres, V., Smith, R. C. & Walsh, K. 1995. MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Mol. Cell. Biol. 15, 38233829.
  • Halevy, O., Novitch, B. G., Spicer, D. B., Skapek, S. X., Rhee, J., Hannon, G. J., Beach, D. & Lassar, A. B. 1995. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science 267, 10181021.
  • Heintz, N. 1993. Cell death and the cell cycle: a relationship between transformation and neurodegeneration? Trends Biochem. Sci. 18, 157159.
  • Herrup, K. & Yang, Y. 2007. Cell cycle regulation in the postmitotic neuron: oxymoron or new biology? Nat. Rev. Neurosci. 8, 368378.
  • Hiebert, S. W., Chellappan, S. P., Horowitz, J. M. & Nevins, J. R. 1992. The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev. 6, 177185.
  • Holt, C. E., Bertsch, T. W., Ellis, H. M. & Harris, W. A. 1988. Cellular determination in the Xenopus retina is independent of lineage and birth date. Neuron 1, 1526.
  • Indovina, P., Marcelli, E., Casini, N., Rizzo, V. & Giordano, A. 2013. Emerging roles of RB family: new defense mechanisms against tumor progression. J. Cell. Physiol. 228, 525535.
  • Itoh, Y., Masuyama, N., Nakayama, K., Nakayama, K. I. & Gotoh, Y. 2007. The cyclin-dependent kinase inhibitors p57 and p27 regulate neuronal migration in the developing mouse neocortex. J. Biol. Chem. 282, 390396.
  • Ji, P., Jiang, H., Rekhtman, K., Bloom, J., Ichetovkin, M., Pagano, M. & Zhu, L. 2004. An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant. Mol. Cell 16, 4758.
  • Johnson, D. A., Donovan, S. L. & Dyer, M. A. 2006. Mosaic deletion of Rb arrests rod differentiation and stimulates ectopic synaptogenesis in the mouse retina. J. Comp. Neurol. 498, 112128.
  • Kapatai, G., Brundler, M. A., Jenkinson, H., Kearns, P., Parulekar, M., Peet, A. C. & McConville, C. M. 2013. Gene expression profiling identifies different sub-types of retinoblastoma. Br. J. Cancer 109, 512525.
  • Kawauchi, T., Chihama, K., Nabeshima, Y. & Hoshino, M. 2006. Cdk5 phosphorylates and stabilizes p27kip1 contributing to actin organization and cortical neuronal migration. Nat. Cell Biol. 8, 1726.
  • Kippin, T. E., Martens, D. J. & Van Der Kooy, D. 2005. p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity. Genes Dev. 19, 756767.
  • Kitagawa, M., Higashi, H., Jung, H. K., Suzuki-Takahashi, I., Ikeda, M., Tamai, K., Kato, J., Segawa, K., Yoshida, E., Nishimura, S. & Taya, Y. 1996. The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2. EMBO J. 15, 70607069.
  • Laurie, N. A., Donovan, S. L., Shih, C. S., Zhang, J., Mills, N., Fuller, C., Teunisse, A., Lam, S., Ramos, Y., Mohan, A., Johnson, D., Wilson, M., Rodriguez-Galindo, C., Quarto, M., Francoz, S., Mendrysa, S. M., Guy, R. K., Marine, J. C., Jochemsen, A. G. & Dyer, M. A. 2006. Inactivation of the p53 pathway in retinoblastoma. Nature 444, 6166.
  • Lein, E. S., Hawrylycz, M. J., Ao, N., Ayres, M., Bensinger, A., Bernard, A., Boe, A. F., Boguski, M. S., Brockway, K. S., Byrnes, E. J., Chen, L., Chen, T. M., Chin, M. C., Chong, J., Crook, B. E., Czaplinska, A., Dang, C. N., Datta, S., Dee, N. R., Desaki, A. L., Desta, T., Diep, E., Dolbeare, T. A., Donelan, M. J., Dong, H. W., Dougherty, J. G., Duncan, B. J., Ebbert, A. J., Eichele, G., Estin, L. K., Faber, C., Facer, B. A., Fields, R., Fischer, S. R., Fliss, T. P., Frensley, C., Gates, S. N., Glattfelder, K. J., Halverson, K. R., Hart, M. R., Hohmann, J. G., Howell, M. P., Jeung, D. P, Johnson, R. A., Karr, P. T., Kawal, R., Kidney, J. M., Knapik, R. H., Kuan, C. L., Lake, J. H., Laramee, A. R., Larsen, K. D., Lau, C., Lemon, T. A., Liang, A. J., Liu, Y., Luong, L. T., Michaels, J., Morgan, J. J., Morgan, R. J., Mortrud, M. T., Mosqueda, N. F., Ng, L. L., Ng, R., Orta, G. J., Overly, C. C., Pak, T. H., Parry, S. E., Pathak, S. D., Pearson, O. C., Puchalski, R. B., Riley, Z. L., Rockett, H. R., Rowland, S. A., Royall, J. J., Ruiz, M. J., Sarno, N. R., Schaffnit, K., Shapovalova, N. V., Sivisay, T., Slaughterbeck, C. R., Smith, S. C., Smith, K. A., Smith, B. I., Sodt, A. J., Stewart, N. N., Stumpf, K. R., Sunkin, S. M., Sutram, M., Tam, A., Teemer, C. D., Thaller, C., Thompson, C. L., Varnam, L. R., Visel, A., Whitlock, R. M., Wohnoutka, P. E., Wolkey, C. K., Wong, V. Y., Wood, M., Yaylaoglu, M. B., Young, R. C., Youngstrom, B. L., Yuan, X. F., Zhang, B., Zwingman, T. A. & Jones, A. R. 2007. Genome-wide atlas of gene expression in the adult mouse brain. Nature 445, 168176.
  • Levine, E. M., Close, J., Fero, M., Ostrovsky, A. & Reh, T. A. 2000. p27(Kip1) regulates cell cycle withdrawal of late multipotent progenitor cells in the mammalian retina. Dev. Biol. 219, 299314.
  • Lukaszewicz, A., Savatier, P., Cortay, V., Giroud, P., Huissoud, C., Berland, M., Kennedy, H. & Dehay, C. 2005. G1 phase regulation, area-specific cell cycle control, and cytoarchitectonics in the primate cortex. Neuron 47, 353364.
  • Macpherson, D., Sage, J., Kim, T., Ho, D., McLaughlin, M. E. & Jacks, T. 2004. Cell type-specific effects of Rb deletion in the murine retina. Genes Dev. 18, 16811694.
  • Mairet-Coello, G., Tury, A., Van Buskirk, E., Robinson, K., Genestine, M. & Dicicco-Bloom, E. 2012. p57(KIP2) regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex. Development 139, 475487.
  • Marques-Torrejon, M. A., Porlan, E., Banito, A., Gomez-Ibarlucea, E., Lopez-Contreras, A. J., Fernandez-Capetillo, O., Vidal, A., Gil, J., Torres, J. & Farinas, I. 2013. Cyclin-dependent kinase inhibitor p21 controls adult neural stem cell expansion by regulating Sox2 gene expression. Cell Stem Cell 12, 88100.
  • McClellan, K. A., Ruzhynsky, V. A., Douda, D. N., et al. 2007. Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions. Mol. Cell. Biol. 27, 48254843.
  • McEvoy, J., Flores-Otero, J., Zhang, J., Nemeth, K., Brennan, R., Bradley, C., Krafcik, F., Rodriguez-Galindo, C., Wilson, M., Xiong, S., Lozano, G., Sage, J., Fu, L., Louhibi, L., Trimarchi, J., Pani, A., Smeyne, R., Johnson, D. & Dyer, M. A. 2011. Coexpression of normally incompatible developmental pathways in retinoblastoma genesis. Cancer Cell 20, 260275.
  • Narita, M., Nunez, S., Heard, E., Lin, A. W., Hearn, S. A., Spector, D. L., Hannon, G. J. & Lowe, S. W. 2003. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113, 703716.
  • Nguyen, L., Besson, A., Heng, J. I., Schuurmans, C., Teboul, L., Parras, C., Philpott, A., Roberts, J. M. & Guillemot, F. 2006. p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex. Genes Dev. 20, 15111524.
  • Nielsen, S. J., Schneider, R., Bauer, U. M., Bannister, A. J., Morrison, A., O'carroll, D., Firestein, R., Cleary, M., Jenuwein, T., Herrera, R. E. & Kouzarides, T. 2001. Rb targets histone H3 methylation and HP1 to promoters. Nature 412, 561565.
  • Novitch, B. G., Mulligan, G. J., Jacks, T. & Lassar, A. B. 1996. Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle. J. Cell Biol. 135, 441456.
  • Oshikawa, M., Okada, K., Nakajima, K. & Ajioka, I. 2013. Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner. Development 140, 23102320.
  • Pajcini, K. V., Corbel, S. Y., Sage, J., Pomerantz, J. H. & Blau, H. M. 2010. Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle. Cell Stem Cell 7, 198213.
  • Pardee, A. B. 1974. A restriction point for control of normal animal cell proliferation. Proc. Natl Acad. Sci. USA 71, 12861290.
  • Parker, S. B., Eichele, G., Zhang, P., Rawls, A., Sands, A. T., Bradley, A., Olson, E. N., Harper, J. W. & Elledge, S. J. 1995. p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science 267, 10241027.
  • Rayman, J. B., Takahashi, Y., Indjeian, V. B., Dannenberg, J. H., Catchpole, S., Watson, R. J., Te Riele, H. & Dynlacht, B. D. 2002. E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex. Genes Dev. 16, 933947.
  • Rockel, A. J., Hiorns, R. W. & Powell, T. P. 1980. The basic uniformity in structure of the neocortex. Brain 103, 221244.
  • Sage, C., Huang, M., Karimi, K., Gutierrez, G., Vollrath, M. A., Zhang, D. S., Garcia-Anoveros, J., Hinds, P. W., Corwin, J. T., Corey, D. P. & Chen, Z. Y 2005. Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. Science 307, 11141118.
  • Sage, J., Miller, A. L., Perez-Mancera, P. A., Wysocki, J. M. & Jacks, T. 2003. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature 424, 223228.
  • Sage, J., Mulligan, G. J., Attardi, L. D., Miller, A., Chen, S., Williams, B., Theodorou, E. & Jacks, T. 2000. Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev. 14, 30373050.
  • Schneider, J. W., Gu, W., Zhu, L., Mahdavi, V. & Nadal-Ginard, B. 1994. Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells. Science 264, 14671471.
  • Sdek, P., Zhao, P., Wang, Y., Huang, C. J., Ko, C. Y., Butler, P. C., Weiss, J. N. & Maclellan, W. R. 2011. Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes. J. Cell Biol. 194, 407423.
  • Sherr, C. J. & Roberts, J. M. 1999. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13, 15011512.
  • Shirodkar, S., Ewen, M., DeCaprio, J. A., Morgan, J., Livingston, D. M. & Chittenden, T. 1992. The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell 68, 157166.
  • Skapek, S. X., Rhee, J., Spicer, D. B. & Lassar, A. B. 1995. Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase. Science 267, 10221024.
  • Smith, E. J., Leone, G., Degregori, J., Jakoi, L. & Nevins, J. R. 1996. The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state. Mol. Cell. Biol. 16, 69656976.
  • Svoboda, D. S., Paquin, A., Park, D. S. & Slack, R. S. 2013. Pocket proteins pRb and p107 are required for cortical lamination independent of apoptosis. Dev. Biol. 384, 101113.
  • Takahashi, Y., Rayman, J. B. & Dynlacht, B. D. 2000. Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression. Genes Dev. 14, 804816.
  • Takai, H., Smogorzewska, A. & De Lange, T. 2003. DNA damage foci at dysfunctional telomeres. Curr. Biol. 13, 15491556.
  • Tarui, T., Takahashi, T., Nowakowski, R. S., Hayes, N. L., Bhide, P. G. & Caviness, V. S. 2005. Overexpression of p27 Kip 1, probability of cell cycle exit, and laminar destination of neocortical neurons. Cereb. Cortex 15, 13431355.
  • Turner, D. L. & Cepko, C. L. 1987. A common progenitor for neurons and glia persists in rat retina late in development. Nature 328, 131136.
  • Tury, A., Mairet-Coello, G. & Dicicco-Bloom, E. 2011. The cyclin-dependent kinase inhibitor p57Kip2 regulates cell cycle exit, differentiation, and migration of embryonic cerebral cortical precursors. Cereb. Cortex 21, 18401856.
  • Weintraub, S. J., Prater, C. A. & Dean, D. C. 1992. Retinoblastoma protein switches the E2F site from positive to negative element. Nature 358, 259261.
  • Xu, X. L., Fang, Y., Lee, T. C., Forrest, D., Gregory-Evans, C., Almeida, D., Liu, A., Jhanwar, S. C., Abramson, D. H. & Cobrinik, D. 2009. Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling. Cell 137, 10181031.
  • Young, R. W. 1985. Cell differentiation in the retina of the mouse. Anat. Rec. 212, 199205.
  • Zacksenhaus, E., Jiang, Z., Chung, D., Marth, J. D., Phillips, R. A. & Gallie, B. L. 1996. pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis. Genes Dev. 10, 30513064.
  • Zetterberg, A. & Larsson, O. 1985. Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells. Proc. Natl Acad. Sci. USA 82, 53655369.
  • Zhang, J., Benavente, C. A., Mcevoy, J., Flores-Otero, J., Ding, L., Chen, X., Ulyanov, A., Wu, G., Wilson, M., Wang, J., Brennan, R., Rusch, M., Manning, A. L., Ma, J., Easton, J., Shurtleff, S., Mullighan, C., Pounds, S., Mukatira, S., Gupta, P., Neale, G., Zhao, D., Lu, C., Fulton, R. S., Fulton, L. L., Hong, X., Dooling, D. J., Ochoa, K., Naeve, C., Dyson, N. J., Mardis, E. R., Bahrami, A., Ellison, D., Wilson, R. K., Downing, J. R. & Dyer, M. A. 2012. A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature 481, 329334.
  • Zhang, J., Gray, J., Wu, L., Leone, G., Rowan, S., Cepko, C. L., Zhu, X., Craft, C. M. & Dyer, M. A. 2004a. Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nat. Genet. 36, 351360.
  • Zhang, J., Schweers, B. & Dyer, M. A. 2004b. The first knockout mouse model of retinoblastoma. Cell Cycle 3, 952959.
  • Zhang, P., Wong, C., Liu, D., Finegold, M., Harper, J. W. & Elledge, S. J. 1999. p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step. Genes Dev. 13, 213224.
  • Zindy, F., Cunningham, J. J., Sherr, C. J., Jogal, S., Smeyne, R. J. & Roussel, M. F. 1999. Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases. Proc Natl Acad Sci USA 96, 1346213467.