These authors share first authorship of this paper.
Neurodevelopmental outcome, psychological adjustment, and quality of life in adolescents with congenital heart disease
Article first published online: 13 AUG 2013
© 2013 Mac Keith Press
Developmental Medicine & Child Neurology
Volume 55, Issue 12, pages 1143–1149, December 2013
How to Cite
Schaefer, C., von Rhein, M., Knirsch, W., Huber, R., Natalucci, G., Caflisch, J., Landolt, M. A. and Latal, B. (2013), Neurodevelopmental outcome, psychological adjustment, and quality of life in adolescents with congenital heart disease. Developmental Medicine & Child Neurology, 55: 1143–1149. doi: 10.1111/dmcn.12242
- Issue published online: 12 NOV 2013
- Article first published online: 13 AUG 2013
- Manuscript Accepted: 24 JUN 2013
- Swiss Heart Foundation
- Else Kröner-Fresenius-Stiftung
The aim of this study was to examine neurodevelopment, psychological adjustment, and health-related quality of life (HRQoL) in adolescents after bypass surgery for congenital heart disease (CHD) during early childhood.
Fifty-nine adolescents (34 females, 25 males) with CHD were examined at a median age of 13 years 8 months (range 11y 5mo–16y 11mo). Outcome was assessed with the Wechsler Intelligence Scale for Children, (fourth edition); the Beery Test of Visual-Motor Integration; the Rey–Osterrieth Complex Figure Test; the Zurich Neuromotor Assessment; the Strengths and Difficulties Questionnaire; and the KIDSCREEN questionnaires. Results were compared with those of 40 age- and sex-matched healthy comparison individuals.
Outcome with regard to full-scale IQ, perceptual reasoning, and the working memory scale was poorer in patients with CHD than in the comparison group (all p≤0.001). Visual perception, visuomotor integration (p≤0.001), and executive functions (Rey figure copy: p=0.05) were also affected. Patients with CHD also had lower scores on all motor domains (p<0.02) except static balance. Psychological adjustment was affected only in the ‘peer relationship’ domain (p=0.05). Quality of life was similar to that of typically developing peers.
Adolescents with CHD may manifest persistent cognitive and motor impairments, while psychological adjustment and self-reported HRQoL are mostly typical. Thus, long-term neurodevelopmental evaluations are necessary to provide early educational and therapeutic support.