Global suppression of electrocortical activity in unilateral perinatal thalamic stroke
Version of Record online: 11 JAN 2014
© 2014 The Authors. Developmental Medicine & Child Neurology published by John Wiley & Sons Ltd on behalf of Mac Keith Press.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Developmental Medicine & Child Neurology
Volume 56, Issue 7, pages 695–698, July 2014
How to Cite
Kharoshankaya, L., Filan, P. M., Bogue, C. O., Murray, D. M. and Boylan, G. B. (2014), Global suppression of electrocortical activity in unilateral perinatal thalamic stroke. Developmental Medicine & Child Neurology, 56: 695–698. doi: 10.1111/dmcn.12365
- Issue online: 12 JUN 2014
- Version of Record online: 11 JAN 2014
- Manuscript Accepted: 12 NOV 2013
- Wellcome Trust. Grant Number: 098983/Z/12/Z
We present an unusual case of persistent generalized electroencephalography (EEG) suppression and right-sided clonic seizures in a male infant born at 40+2 weeks' gestation, birthweight 3240g, with an isolated unilateral thalamic stroke. The EEG at 13 hours after birth showed a generalized very low amplitude background pattern, which progressed to frequent electrographic seizures over the left hemisphere. The interictal background EEG pattern remained grossly abnormal over the next 48 hours, showing very low background amplitudes (<10μV). Magnetic resonance imaging revealed an isolated acute left-sided thalamic infarction. This is the first description of severe global EEG suppression caused by an isolated unilateral thalamic stroke and supports the role of the thalamus as the control centre for cortical electrical activity.