Non-linear association between 25-hydroxyvitamin D and the incidence of Type 2 diabetes: a community-based nested case–control study (pages 934–938)
M. Tohidi, M. Bozorgmanesh, R. Mohebi, D. Khalili, N. Saadat, N. Khorrami, F. Azizi and F. Hadaegh
Version of Record online: 7 APR 2013 | DOI: 10.1111/dme.12180
- Few prospective studies, having measured baseline serum 25-hydroxyvitamin D [25(OH)D], have studied the association between vitamin D status and the risk of newly diagnosed Type 2 diabetes.
- Given the fact that 25(OH)D deficiency and Type 2 diabetes co-exist with a high prevalence among the Middle Eastern population, investigating if and how serum 25(OH)D concentrations contribute to the Type 2 diabetes incidence rate might be warranted. Using a community-based prospective study, we sought to examine the following: first, if serum 25(OH)D contributed to newly diagnosed Type 2 diabetes; and second, if a cutoff-point in the concentrations of 25(OH)D could be determined for identifying subjects at increased risk of Type 2 diabetes.