The center received free electrodes and technical equipment for the treatment of study patients from IGEA, Germany.
Electrochemotherapy Under Tumescent Local Anesthesia for the Treatment of Cutaneous Metastases
Article first published online: 6 MAR 2013
© 2013 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.
Volume 39, Issue 7, pages 1023–1032, July 2013
How to Cite
Kendler, M., Micheluzzi, M., Wetzig, T. and Simon, J. C. (2013), Electrochemotherapy Under Tumescent Local Anesthesia for the Treatment of Cutaneous Metastases. Dermatologic Surgery, 39: 1023–1032. doi: 10.1111/dsu.12190
- Issue published online: 1 JUL 2013
- Article first published online: 6 MAR 2013
The surgical management of cutaneous metastasis (CM) is challenging, particularly in elderly patients, in whom general anesthesia can be difficult because of comorbidity.
To test the effectiveness of tumescent local anesthesia (TLA) to achieve adequate anesthesia during the treatment of extensive CM with electrochemotherapy (ECT), previously only performed under general anesthesia.
We conducted five ECT treatments of CM with intralesional bleomycin under TLA. We examined pain scores before, during, and after treatment; analgesic use; and side effects. The intention of the treatment was palliative in all cases.
We treated four patients (ages 75–88) with CM with a mean area of 126 cm2 (range 12–198 cm2) with 356 mL of TLA per treatment (range 180–450 mL). The ECT treatment under TLA demonstrated that anesthesia was adequate, with moderate pain during and slight pain after the procedure as measured on a visual analog scale (VAS).
In this proof-of-principle study, we demonstrated that ECT can be performed under TLA; TLA might be a useful new anesthesia option for patients treated with ECT.