The authors have indicated no significant interest with commercial supporters.
Evaluation of Effectiveness of Cryotherapy on the Treatment of Cutaneous Kaposi's Sarcoma
Article first published online: 23 JUL 2013
© 2013 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.
Volume 39, Issue 10, pages 1502–1506, October 2013
How to Cite
Kutlubay, Z., Küçüktaş, M., Yardımcı, G., Engin, B. and Serdaroğlu, S. (2013), Evaluation of Effectiveness of Cryotherapy on the Treatment of Cutaneous Kaposi's Sarcoma. Dermatologic Surgery, 39: 1502–1506. doi: 10.1111/dsu.12285
- Issue published online: 1 OCT 2013
- Article first published online: 23 JUL 2013
Kaposi's sarcoma (KS) is a vascular tumor that affects the skin and other organs. Several therapeutic options are available, but the optimal therapy is unclear. The aim of this study was to determine the effectiveness and safety of cryotherapy in the treatment of KS.
Materials and Methods
Thirty patients were evaluated. Cryotherapy was applied using liquid nitrogen. Each treatment consisted of two freeze–thaw cycles, with freezing times ranging from 15 to 40 seconds per cycle.
One hundred twenty-five lesions were treated in an average of 3.2 sessions. Complete response was observed in 19 (63%) of the 30 patients after cryotherapy treatment with no recurrence. The subjects tolerated cryotherapy well. Blistering occurred frequently, but local pain was limited. There were no secondary infections.
Liquid nitrogen cryotherapy is safe and cost-efficient and can be readily adopted as an effective primary therapy for cutaneous KS lesions that respond slowly or show incomplete cosmetic improvement after systemic therapies.