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Fissured tongue responding to biologics during the treatment of psoriasis: the importance of detecting oral involvement of psoriasis


Address correspondence and reprint requests to: Angelo Massimiliano D'Erme, MD, Division of Dermatology, Department of Surgery and Translational Medicine, University of Florence, Piazza di Indipendenza 11, 50129 Florence, Italy, or email:


Recent studies have provided more evidence that psoriasis can give mucosal lesions, especially oral. Nonspecific lesions such as fissured tongue and geographic tongue are relatively frequent in patients suffering from psoriasis. We report a case of a patient presenting an important improvement of his fissured tongue paralleling the improvement of the cutaneous lesions after a 5-month systemic therapy with infliximab. The authors think it would be important to consider possible oral lesions in patients suffering from psoriasis in normal practice and to evaluate them introducing specific clinical scales.