Desferrioxamine treatment of porphyria cutanea tarda in a patient with HIV and chronic renal failure
Article first published online: 6 JUN 2013
© 2013 Wiley Periodicals, Inc.
Volume 27, Issue 1, pages 16–18, January/February 2014
How to Cite
Vasconcelos, P., Luz-Rodrigues, H., Santos, C. and Filipe, P. (2014), Desferrioxamine treatment of porphyria cutanea tarda in a patient with HIV and chronic renal failure. Dermatologic Therapy, 27: 16–18. doi: 10.1111/dth.12024
- Issue published online: 6 FEB 2014
- Article first published online: 6 JUN 2013
- chronic renal failure;
- porphyria cutanea tarda
Porphyria cutanea tarda (PCT) can occur in HIV patients. Current evidence suggests that HIV infection may interfere with the hepatic cytochrome oxidase system, leading to porphyrin metabolism impairment. Moreover, chronic hemodialysis in renal failure may be a risk factor for PCT. In addition to the contributory factors for PCT associated to HIV infection, it is possible that porphyrin accumulation secondary to renal failure may play a role in the expression of this disease. We report a case of PCT in an HIV-1 infected patient under blood dialysis, refractory to antimalarials and controlled with desferrioxamine.