Article first published online: 6 JUN 2013
© 2013 Wiley Periodicals, Inc.
Special Issue: Update on Understanding and Managing Chronic Wounds
Volume 26, Issue 3, pages 222–235, May/June 2013
How to Cite
Hoffman, M. D. (2013), Atypical ulcers. Dermatologic Therapy, 26: 222–235. doi: 10.1111/dth.12048
- Issue published online: 6 JUN 2013
- Article first published online: 6 JUN 2013
- atypical ulcer;
- skin ulcer;
Atypical ulcers of the skin challenge the dermatologist with respect to recognition, diagnosis, management, and treatment. The entire gamut of pathogenic categories including vascular, inflammatory, neoplastic, genetic, medication-related, and infectious processes may give rise to atypical ulcers. By definition, these ulcers are unusual, and accurate diagnosis may ultimately require the clinician to violate the dictum that “common things are common.” Atypical ulcers may present with features that the clinician has not previously encountered, or may present with seemingly typical features that actually mislead due to phenotypic mimicry. Because skin ulcers are inherently tissue-destructive, and may reflect an underlying systemic disease process, there is heightened urgency to achieving an accurate diagnosis and initiating appropriate therapy.