Churg–Strauss Syndrome Associated with Rapid Deterioration of Left Ventricular Diastolic Dysfunction and Conduction Disturbance
Article first published online: 30 JUL 2013
© 2013, Wiley Periodicals, Inc.
Volume 30, Issue 9, pages E269–E273, October 2013
How to Cite
- Issue published online: 8 OCT 2013
- Article first published online: 30 JUL 2013
- Churg–Strauss syndrome;
- left ventricular dysfunction;
- cardiac conduction defect
Cardiac involvement in Churg–Strauss syndrome (CSS) is a major cause of mortality. Here we report a case of a 75-year-old woman with eosinophilic endomyocarditis due to CSS. An electrocardiogram showed intraventricular conduction delay, and echocardiography showed an impaired relaxation pattern and biventricular apical thickening. Magnetic resonance imaging revealed subendocardial delayed enhancement with biventricular apical thrombi. Endomyocardial biopsy showed perivascular eosinophilic infiltration. Despite resolution of the hypereosinophilia after steroid therapy, her left ventricular (LV) diastolic function worsened into a restrictive pattern and she died with a ventricular escape rhythm on her 14th day in the hospital. This case is unusual in that there was rapid progression of the LV diastolic dysfunction and conduction disturbance due to CSS.