Metabolic syndrome in antipsychotic naïve patients with schizophrenia: pooled analysis of data from three Indian studies
Article first published online: 20 JAN 2014
© 2014 Wiley Publishing Asia Pty Ltd
Early Intervention in Psychiatry
How to Cite
Grover, S., Nebhinani, N., Padmavati, R., Chadda, R. K., Tirupati, S. and Pallava, A. (2014), Metabolic syndrome in antipsychotic naïve patients with schizophrenia: pooled analysis of data from three Indian studies. Early Intervention in Psychiatry. doi: 10.1111/eip.12117
- Article first published online: 20 JAN 2014
- Manuscript Accepted: 7 DEC 2013
- Manuscript Received: 24 AUG 2013
- drug naïve;
- metabolic syndrome;
This study aimed to assess the prevalence of metabolic syndrome (MS) and subthreshold MS in antipsychotic naïve patients with schizophrenia by pooling the data from three different centres in India.
One hundred thirty-seven antipsychotic naïve patients with schizophrenia were evaluated for MS using common criteria for clinical diagnosis.
Twenty-six patients (19%) met consensus criteria. Additionally, 56 patients (40.9%) fulfilled one criterion and 32 patients (23.3%) fulfilled two criteria of MS out of five criteria.
One-fifth of antipsychotic naïve patients with schizophrenia had MS and another two-third had at least one metabolic abnormality. Awareness of such a high risk is vitally important for rational selection of antipsychotic medications as well as effective implementation of preventive measures.