Structural evidence of α-aminoacylated lipoproteins of Staphylococcus aureus (pages 716–728)
Miwako Asanuma, Kenji Kurokawa, Rie Ichikawa, Kyoung-Hwa Ryu, Jun-Ho Chae, Naoshi Dohmae, Bok Luel Lee and Hiroshi Nakayama
Version of Record online: 12 JAN 2011 | DOI: 10.1111/j.1742-4658.2010.07990.x
The determination of exact lipidated structures of Staphylococcus aureus lipoproteins is crucial for elucidating the molecular basis of the interaction of host microorganisms. Based on analytical data of lipoprotein lipase treatment and tandem mass spectrometry (MS/MS), we demonstrate that major lipoproteins of S. aureus are mainly in the N-acylated triacyl form, suggesting that S. aureus has an unidentified enzyme catalyzing N-acylation of diacylated lipoproteins.
Vol. 278, Issue 7, 1186, Version of Record online: 9 MAR 2011