High-fat diet acutely affects circadian organisation and eating behavior (pages 1350–1356)
Julie S. Pendergast, Katrina L. Branecky, William Yang, Kate L. J. Ellacott, Kevin D. Niswender and Shin Yamazaki
Version of Record online: 21 JAN 2013 | DOI: 10.1111/ejn.12133
The effects of 1 week of high-fat diet consumption on tissue and behavioral circadian rhythms in mice were investigated. The phase of the liver rhythm was advanced, while rhythms in other tissues were not affected by high-fat diet. High-fat diet also immediately altered the daily rhythm of eating behavior. As the rhythm of the suprachiasmatic nucleus (SCN) was not affected, the brain nuclei mediating the effect of high-fat diet on eating behavior are likely downstream of the SCN.