Visual cortex organisation in a macaque monkey with macular degeneration (pages 3456–3464)
Yibin Shao, Georgios A. Keliris, Amalia Papanikolaou, M. Dominik Fischer, Ditta Zobor, Herbert Jägle, Nikos K. Logothetis and Stelios M. Smirnakis
Version of Record online: 23 AUG 2013 | DOI: 10.1111/ejn.12349
FMRI study on a macaque monkey with macular degeneration suggests that the border of the V1 lesion projection zone remained stable while population receptive field (pRF) size of non-deafferented V1 increased slightly. Remarkably, V5/MT of the MD animal showed extensive activation compared to controls with pRF size distributions differing markedly. These results suggest that V5/MT has a higher potential for reorganisation after macular degeneration than earlier visual cortex.