These authors contributed equally to this work.
Impaired sexual activity in young ischaemic stroke patients: an observational study
Article first published online: 7 OCT 2013
© 2013 The Author(s) European Journal of Neurology © 2013 EFNS
European Journal of Neurology
Volume 21, Issue 1, pages 140–146, January 2014
How to Cite
Bugnicourt, J.-M., Hamy, O., Canaple, S., Lamy, C. and Legrand, C. (2014), Impaired sexual activity in young ischaemic stroke patients: an observational study. European Journal of Neurology, 21: 140–146. doi: 10.1111/ene.12277
- Issue published online: 10 DEC 2013
- Article first published online: 7 OCT 2013
- Manuscript Accepted: 3 SEP 2013
- Manuscript Received: 4 JUL 2013
- ischaemic stroke;
- sexual disorders;
Background and purpose
The present study sought to determine the impact of stroke on sexual function and well-being in a cohort of young ischaemic stroke patients and identify factors associated with impairment.
Over a 2-year period, all patients aged 60 or under with ischaemic stroke or transient ischaemic attack (n = 156) were included. Information on sexual function and well-being was obtained by means of a paper questionnaire mailed to participants 1 year after their stroke. Impaired sexual activity (ISA) was defined as a decline in sexual function and/or satisfaction. Psychological well-being was evaluated on the Hospital Anxiety and Depression Scale (HADS).
The response rate was 67% (n = 104). Thirty of these responders (29%) reported ISA. Patients with ISA had a higher HADS score (19.7 vs. 11.2 in patients with no impairment; P < 0.001), anxiety score (10.0 vs. 6.3; P < 0.001) and depression score (8.7 vs. 4.8; P < 0.001) and were more likely to have left brain lesions (70% vs. 30%; P < 0.001) and use angiotensin-converting enzyme (ACE) inhibitors (73% vs. 31%; P < 0.001) and diuretics (50% vs. 19%; P = 0.003). In a stepwise logistic regression, depression (odds ratio 9.1, 95% confidence interval 2.45−33.46; P = 0.001) and ACE inhibitor use (odds ratio 6.0, 95% confidence interval 2.11−17.28; P = 0.001) were associated with ISA.
Impaired sexual activity was reported by almost one-third of younger patients 1 year after ischaemic stroke. Factors associated with post-stroke ISA may include specific medications and depression rather than the characteristics of the stroke per se.