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Appendix S1. Screening tools at age 18 and 36 months.

Table S1. Risk of adverse development score at 18 and 36 months in children with antiepileptic drug (AED) exposure in utero compared to (1) matched controls and (2) all references.

Table S2. Risk of adverse development score at 18 and 36 months in children with lamotrigine (LTG) exposure in utero compared to (1) matched controls and (2) all references.

Table S3. Risk for adverse birth outcome in children of parents with epilepsy compared to a reference group of children of parents without epilepsy.

Table S4. Risk of adverse development in children exposed to antiepileptic drugs (AEDs) in utero compared to children of parents without epilepsy.

Table S5. Maternal characteristics of children exposed to antiepileptic drugs in utero, comparing children with included and missing data (lost to follow-up) at 18 and 36 months of age.

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