Full-Length Original Research
Theory of mind and epilepsy: What clinical implications?
Article first published online: 28 JUN 2013
Wiley Periodicals, Inc. © 2013 International League Against Epilepsy
Volume 54, Issue 9, pages 1639–1646, September 2013
How to Cite
Giovagnoli, A. R., Parente, A., Villani, F., Franceschetti, S. and Spreafico, R. (2013), Theory of mind and epilepsy: What clinical implications?. Epilepsia, 54: 1639–1646. doi: 10.1111/epi.12255
- Issue published online: 6 SEP 2013
- Article first published online: 28 JUN 2013
- Manuscript Accepted: 20 MAY 2013
- Theory of mind;
- Psychobehavioral disturbances;
- Cognitive self-evaluation;
- Quality of life
Epilepsy can impair theory of mind (ToM), but the clinical significance of such a deficit is unknown. This study evaluated the influence of selective ToM deficits on self-appraisal, coping, and quality of life (QoL) in patients with focal epilepsy.
Data were collected from 66 patients with temporal or frontal lobe epilepsy, and from 42 healthy controls. The Faux Pas Task (FPT), Multiple Ability Self-report Questionnaire (MASQ), Coping Responses Inventory-Adult (CRI-Adult), and World Health Organization QoL 100 (WHOQoL 100) evaluated ToM, self-rated cognitive abilities, coping to stressful events, and QoL. Different tests and inventories assessed other cognitive functions, depression, and anxiety.
Patients were impaired in the recognition and comprehension of social faux pas. The FPT scores contributed to predict the MASQ, CRI-Adult, and WHOQoL overall scores; the comprehension of others' mental states and interactions score exerted a prominent influence.
In patients with focal epilepsy, selective ToM deficits may have clinical implications, with specific influence on self-appraisal, coping, and overall QoL. ToM evaluation may contribute in explaining some psychobehavioral difficulties and to plan nonpharmacological treatment.