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Keywords:

  • CNS neoplasm;
  • Glioma;
  • O6-methylguanine DNA methyltransferase;
  • Temozolomide;
  • Bevacizumab

Summary

I present an overview of therapy for the most common brain tumors encountered in clinical practice if adult patients. Current therapy paradigms and evolving therapies are reviewed. The introduction of non–enzyme-inducing antiepileptic drugs (NEIADs) has simplified the approach to combined medical treatment of epilepsy and brain tumors, but the major interactions between enzyme-inducing antiepileptic drugs (EIAEDs) are included, to serve as guidance in selecting these medications if they are required.