Full-Length Original Research
Screening of major depression in epilepsy: The Neurologic Depression Disorders Inventory in Epilepsy-Spanish version (Argentina)
Article first published online: 12 FEB 2014
Wiley Periodicals, Inc. © 2014 International League Against Epilepsy
Volume 55, Issue 2, pages 331–334, February 2014
How to Cite
Epilepsia, 55(2):331–334, 2014
- Issue published online: 12 FEB 2014
- Article first published online: 12 FEB 2014
- Manuscript Accepted: 1 NOV 2013
- Major depressive disorder;
- Treatment-resistant epilepsy;
- Mini International Neuropsychiatric Inventory;
- Antidepressant drugs;
- Focal epilepsy;
- Generalized epilepsy
To validate and translate the English version of the Neurologic Depression Disorders Inventory in Epilepsy (NDDI-E) into Spanish as a screening instrument for major depressive episodes (MDE) for patients with epilepsy from Argentina and Uruguay.
One hundred fifty-five consecutive outpatients with epilepsy participated in this study. The module of MDE of the MINI International Neuropsychiatric Instrument (MINI Plus version) was used as the gold standard against which the translated version of the NDDI-E was validated.
Among the 155 patients, 25 (16%) met Diagnostic and Statistical Manual, Fourth Edition (DSM-IV) criteria for MDE according to the MINI. With a total score of >15, The NDDI-E identified MDE with an 80% sensitivity, 90% specificity, 60% positive predictive value, and 95.5% negative predictive value.
These data indicate that the Spanish version of the NDDI-E can reliably identify MDE in patients with epilepsy from Argentina and Uruguay.