Fight evolution with evolution: plasmid-dependent phages with a wide host range prevent the spread of antibiotic resistance
Article first published online: 10 JUN 2013
© 2013 The Authors. Published by John Wiley & Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Volume 6, Issue 6, pages 925–932, September 2013
How to Cite
Ojala, V., Laitalainen, J. and Jalasvuori, M. (2013), Fight evolution with evolution: plasmid-dependent phages with a wide host range prevent the spread of antibiotic resistance. Evolutionary Applications, 6: 925–932. doi: 10.1111/eva.12076
- Issue published online: 27 AUG 2013
- Article first published online: 10 JUN 2013
- Manuscript Accepted: 26 APR 2013
- Manuscript Received: 11 JAN 2013
- Academy of Finland Centre of Excellence
- Academy of Finland
Figure S1. Bacterial growth curves illustrating the effects of lethal and non-lethal antibiotic selection on bacterial growth.
Table S1. Arcsine transformed mean frequencies (± standard deviation) of multi-resistant (kanamycin and rifampicin) bacteria) in different antibiotic treatments divided into experimental days, and statistical comparisons (1-way anova) between phage-containing and phage-free treatments.
Table S2. Mean total number (± standard deviation) of bacteria (colony-forming units per milliliter; cfu/mL) in different antibiotic treatments divided into experimental days.
Table S3. Mean number (± standard deviation) of PRD1 phage particles (particle-forming units per millilitre; pfu/mL) present in different antibiotic treatments at the end of the experiment.
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