ANALYTICAL CLINICAL STUDIES
Distribution and predictive factors of seizure types in 104 cases
Article first published online: 30 OCT 2013
© 2013 EVJ Ltd
Equine Veterinary Journal
Volume 46, Issue 4, pages 441–445, July 2014
How to Cite
Lacombe, V. A., Mayes, M., Mosseri, S., Reed, S. M. and Ou, T. H. (2014), Distribution and predictive factors of seizure types in 104 cases. Equine Veterinary Journal, 46: 441–445. doi: 10.1111/evj.12149
- Issue published online: 9 JUN 2014
- Article first published online: 30 OCT 2013
- Accepted manuscript online: 26 JUL 2013 05:03AM EST
- Manuscript Accepted: 14 JUL 2013
- Manuscript Received: 18 MAR 2013
- generalised seizure;
- focal seizure;
Reasons for performing the study
Although many studies have been performed to classify seizures by type in man and small animals, a similar study in horses is lacking.
The aims of this study were as follows: 1) to characterise the distribution of seizure types in 104 horses presented for seizure disorders to a referral veterinary hospital; and 2) to characterise the various types of seizures by identifying associated clinical factors.
Retrospective analysis of clinical records.
Seizures were classified based on seizure type, according to the most recent accepted definitions in both human and small animal epileptology. History, clinical and neurological examinations, diagnostic investigations and post mortem examinations, when available, were recorded for univariable and multivariable logistic regression analyses.
Seizures were categorised as primary generalised in 23% of horses, focal without secondary generalisation in 42% of cases and secondary generalised in 24% of cases. The type of seizure could not be classified in 11% of cases. Significant associations were found between seizure type and the following characteristics: 1) gender; 2) frequency of seizures; and 3) presence of seizures during hospitalisation. Seizure type was not significantly associated with aetiology. For a horse with recurrent seizures, the odds of having focal seizures was 3.7 times higher (P = 0.02) than in a similar horse with nonrecurring seizures in the final logistic regression model.
The majority of the seizures described were focal seizures with or without secondary generalisation. The clinical presentation was independent of the underlying disease.