Elasticity and breaking strength of synthetic suture materials incubated in various equine physiological and pathological solutions
Article first published online: 20 NOV 2013
© 2013 EVJ Ltd
Equine Veterinary Journal
How to Cite
Kearney, C. M., Buckley, C. T., Jenner, F., Moissonnier, P. and Brama, P. A. J. (2013), Elasticity and breaking strength of synthetic suture materials incubated in various equine physiological and pathological solutions. Equine Veterinary Journal. doi: 10.1111/evj.12181
- Article first published online: 20 NOV 2013
- Accepted manuscript online: 4 SEP 2013 08:27AM EST
- Manuscript Accepted: 22 AUG 2013
- Manuscript Received: 2 MAY 2013
- Veterinary Clinical Sciences Unit in the School of Veterinary Medicine, University College Dublin
- suture material;
- breaking strength
Reasons for performing study
Selection of suture material in equine surgery is often based on costs or subjective factors, such as the surgeon's personal experience, rather than objective facts. The amount of objective data available on durability of suture materials with regard to specific equine physiological conditions is limited.
To evaluate the effect of various equine physiological and pathological fluids on the rate of degradation of a number of commonly used suture materials.
In vitro material testing.
Suture materials were exposed in vitro to physiological fluid, followed by biomechanical analysis. Three absorbable suture materials, glycolide/lactide copolymer, polyglactin 910 and polydioxanone were incubated at 37°C for 7, 14 or 28 days in phosphate-buffered saline, equine serum, equine urine and equine peritoneal fluid from an animal with peritonitis. Five strands of each suture material type were tested to failure in a materials testing machine for each time point and each incubation medium. Yield strength, strain and Young's modulus were calculated, analysed and reported.
For all suture types, the incubation time had a significant effect on yield strength, percentage elongation and Young's modulus in all culture media (P<0.0001). Suture type was also shown significantly to influence changes in each of yield strength, percentage elongation and Young's modulus in all culture media (P<0.0001). While the glycolide/lactide copolymer demonstrated the highest Day 0 yield strength, it showed the most rapid degradation in all culture media. For each of the 3 material characteristics tested, polydioxanone showed the least variation across the incubation period in each culture medium.
The duration of incubation and the type of fluid have significant effects on the biomechanical properties of various suture materials. These findings are important for evidence-based selection of suture material in clinical cases.