EVOLUTION OF TRANSCRIPTION NETWORKS IN RESPONSE TO TEMPORAL FLUCTUATIONS
Version of Record online: 20 DEC 2012
© 2012 The Author(s). Evolution© 2012 The Society for the Study of Evolution.
Volume 67, Issue 4, pages 1091–1104, April 2013
How to Cite
Roh, K., Safaei, F. R. P., Hespanha, J. P. and Proulx, S. R. (2013), EVOLUTION OF TRANSCRIPTION NETWORKS IN RESPONSE TO TEMPORAL FLUCTUATIONS. Evolution, 67: 1091–1104. doi: 10.1111/evo.12012
- Issue online: 3 APR 2013
- Version of Record online: 20 DEC 2012
- Accepted manuscript online: 21 NOV 2012 08:57AM EST
- Received November 8, 2011 Accepted October 23, 2012 Data Archived: doi: 10.5061/dryad.fg868
- Genetic Networks;
- Population Genetics;
Organisms respond to changes in their environment over a wide range of biological and temporal scales. Such phenotypic plasticity can involve developmental, behavioral, physiological, and genetic shifts. The adaptive value of a plastic response is known to depend on the nature of the information that is available to the organism as well as the direct and indirect costs of the plastic response. We modeled the dynamic process of simple gene regulatory networks as they responded to temporal fluctuations in environmental conditions. We simulated the evolution of networks to determine when genes that function solely as transcription factors, with no direct function of their own, are beneficial to the function of the network. When there is perfect information about the environment and there is no timing information to be extracted then there is no advantage to adding pure transcription factor genes to the network. In contrast, when there is either timing information that can be extracted or only indirect information about the current state of the environment then additional transcription factor genes improve the evolved network fitness.