THE IMPORTANCE OF MOSQUITO BEHAVIOURAL ADAPTATIONS TO MALARIA CONTROL IN AFRICA
Article first published online: 15 FEB 2013
© 2013 The Author(s). Evolution© 2013 The Society for the Study of Evolution.
Volume 67, Issue 4, pages 1218–1230, April 2013
How to Cite
Gatton, M. L., Chitnis, N., Churcher, T., Donnelly, M. J., Ghani, A. C., Godfray, H. C. J., Gould, F., Hastings, I., Marshall, J., Ranson, H., Rowland, M., Shaman, J. and Lindsay, S. W. (2013), THE IMPORTANCE OF MOSQUITO BEHAVIOURAL ADAPTATIONS TO MALARIA CONTROL IN AFRICA. Evolution, 67: 1218–1230. doi: 10.1111/evo.12063
- Issue published online: 3 APR 2013
- Article first published online: 15 FEB 2013
- Accepted manuscript online: 1 FEB 2013 07:16AM EST
- Received September 6, 2012 Accepted January 12, 2013
- indoor residual spraying;
- insecticidal nets;
Over the past decade the use of long-lasting insecticidal nets (LLINs), in combination with improved drug therapies, indoor residual spraying (IRS), and better health infrastructure, has helped reduce malaria in many African countries for the first time in a generation. However, insecticide resistance in the vector is an evolving threat to these gains. We review emerging and historical data on behavioral resistance in response to LLINs and IRS. Overall the current literature suggests behavioral and species changes may be emerging, but the data are sparse and, at times unconvincing. However, preliminary modeling has demonstrated that behavioral resistance could have significant impacts on the effectiveness of malaria control. We propose seven recommendations to improve understanding of resistance in malaria vectors. Determining the public health impact of physiological and behavioral insecticide resistance is an urgent priority if we are to maintain the significant gains made in reducing malaria morbidity and mortality.