In Verweij et al. (2012), there is a typographical error in Table 1. The heading of the 3rd column in Table 1 should read ‘% VA due to common variants (MAF > .01)’. The published version reads ‘… (MAF > .1)’. The correct table is below:

Table 1. Predictions from evolutionary models for maintenance of genetic variation in complex traits
 No. of causal% VA due to common variants  InbreedingUseful
Modelvariantsa(MAF > .01)VNA/VGbh2(SNPs)/H2affects traitreferences
  1. VA additive genetic variation; VNA: nonadditive genetic variation; MAF: minor allele frequency

  2. a

    Previous research strongly suggests a highly polygenic basis to personality (Verweij et al. 2010)

  3. b

    VNA/VG is expected to be fairly low under neutrality (Hill et al. 2008), though no specific level can be predicted; ‘higher’ predicted levels are in comparison this baseline

  4. c

    Yes under directional selection, no under stabilising selection

  5. d

    These predictions appear to approximately generalise to overdominance in general (Burger 2000)

  6. e

    Inbreeding is expected to decrease fitness, but does not necessarily affect the trait in question

Selective neutralityNo prediction98%LowHighNo(Eyre-Walker 2010)
Mutation-selection balanceMany<<98%HigherLowPossiblyc(Eyre-Walker 2010)
Balancing selection      
 pleiotropic balancing selectionNo prediction>98%LowHighNo(Turelli and Barton 2004)
environmental heterogeneityNo prediction>98%LowHighNo(Turelli and Barton 2004)
negative frequency-dependent selectionFew>98%LowHighNo(Mani et al. 1990; Kopp and Hermisson 2006)
sex-dependent selectionUp to two>98%LowHighNo(Turelli and Barton 2004)
overdominance for fitness, resulting from antagonistic pleiotropydFew>98%HigherLowPossiblye(Curtsinger et al. 1994; Hedrick 1999; Burger 2000)


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  • Verweij, K. J. H., Yang, J., Lahti, J., Veijola, J., Hintsanen, M., Pulkki-Råback, L., Heinonen, K., Pouta, A., Pesonen, A.-K., Widen, E., Taanila, A., Isohanni, M., Miettunen, J., Palotie, A., Penke, L., Service, S. K., Heath, A. C., Montgomery, G. W., Raitakari, O., Kähönen, M., Viikari, J., Räikkönen, K., Eriksson, J. G., Keltikangas-Järvinen, L., Lehtimäki, T., Martin, N. G., Järvelin, M.-R., Visscher, P. M., Keller, M. C. and Zietsch, B. P. 2012. Maintenance of variation in human personality: testing evolutionary models by estimating heritability due to common causal variants and investigating the effect of distant inbreeding. Evolution, 66:32383251. doi: 10.1111/j.1558-5646.2012.01679.x.