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Figure S1. (A) Plot of the distribution of resampled ICV values for each mammalian family. Range of the distribution is proportional to the degree of uncertainty in the ICV estimate. Results are shown for 100 resamplings. (B) Plot of the distribution of resampled ICV values for each mammalian family after the adjustment suggested by Young et al. (2010).

Figure S2. Plot of the distribution of resampled Flexibility and Constraints indexes for each mammalian family.

Figure S3. Distribution of pairwise vector correlations among the pmax of the different mammalian families.

Figure S4. (A) Average vector correlation between each family pmax and that of other families plotted against the deviations of the observed flexibility values from theoretical expectations. (B) Flexibility index calculated from residual matrices plotted against the deviations of the observed flexibility values from theoretical expectations.

Table S1. Skull measurements (see Fig. 2 for acronyms) and their association with the theoretical modularity hypotheses for each order.

Table S2. Variables measured for the simulation involving the V/CV matrix of each taxon with altered proportions of size variation.

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