Turning acne on/off via mTORC1
Article first published online: 25 JUN 2013
© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Volume 22, Issue 7, pages 505–506, July 2013
How to Cite
Danby, F. W. (2013), Turning acne on/off via mTORC1. Experimental Dermatology, 22: 505–506. doi: 10.1111/exd.12180
- Issue published online: 25 JUN 2013
- Article first published online: 25 JUN 2013
- Accepted manuscript online: 30 MAY 2013 10:24AM EST
- Manuscript Accepted: 27 MAY 2013
Over the past 10 years, the increase in comprehension of the mechanisms behind acne has been truly exponential. Starting with the ethnological work of Cordain, accelerated by the epidemiological work of Adebamowo, supported by the clinical trials of Smith and Mann, Kwon, DiLandro and others, the interface of diet and acne is coming into focus. Melnik now presents an exceptional pair of papers that illustrate for dermatologists what translational research is all about. The Western diet, the role of dairy, FoxO1 and mTORC1, the interplay of agonists and antagonists, therapeutics present and future – the jigsaw puzzle is coming together.