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Fig. S1. The conversion of Ang I to Ang II (A, B) and the stability of Ang II (C, D) in the presence of recombinant AnCE.

Fig. S2. Sequential cleavage of Thr6–BK by AnCE.

Fig. S3. (A) Thr6–BK-bound AnCE crystal structure. AnCE (cyan), with Thr6–BK in magenta sticks. Citrate ion in grey. (B) Schematic view of Thr6–BK. Binding with hydrophobic interactions, hydrogen bonds and distances cited (grey).

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