SEARCH

SEARCH BY CITATION

References

  • 1
    Berry SJ, Coffey DS, Walsh PC & Ewing LL (1984) The development of human benign prostatic hyperplasia with age. J Urol 132, 474479.
  • 2
    Steers WD (2001) 5alpha-reductase activity in the prostate. Urology 58, 1724.
  • 3
    Wright AS, Thomas LN, Douglas RC, Lazier CB & Rittmaster RS (1996) Relative potency of testosterone and dihydrotestosterone in preventing atrophy and apoptosis in the prostate of the castrated rat. J Clin Invest 98, 25582563.
  • 4
    Pelletier G (2002) Effects of estradiol on prostate epithelial cells in the castrated rat. J Histochem Cytochem 50, 15171524.
  • 5
    Petrow V (1986) The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications. Prostate 9, 343361.
  • 6
    Xu Y, Dalrymple SL, Becker RE, Denmeade SR & Isaacs JT (2006) Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers. Clin Cancer Res 12, 40724079.
  • 7
    Rusell DW & Wilson JD (1994) Steroid 5alpha-reductase. Two genes/two enzymes. Annu Rev Biochem 63, 2561.
  • 8
    Mahendroo MS, Cala KM, Hess DV & Rusell DW (2001) Unexpected virilization in male mice lacking steroid 5α-reductase enzymes. Endocrinology 142, 46524662.
  • 9
    Torres JM, Ruíz E & Ortega E (2003) Development of a quantitative RT-PCR method to study 5α-reductase mRNA isozymes in rat prostate in different androgen status. Prostate 5, 674679.
  • 10
    Iehle C, Radvanyi F, Gil Diez de Medina S, Ouafik LH, Gerard H, Chopin D, Raynaud JP & Martin PM (1999) Differences in steroid 5α-reductase isoenzymes expression between normal and pathological human prostate tissue. J Steroid Biochem Mol Biol 68, 189195.
  • 11
    Bruchovsky N, Rennie PS, Batzold FH, Goldenberg SL, Fletcher T & McLoughlin MG (1988) Kinetic parameters of 5 alpha-reductase activity in stroma and epithelium of normal, hyperplastic, and carcinomatous human prostates. J Clin Endocrinol Metab 67, 806816.
  • 12
    Febbo PG, Kantoff PW, Platz EA, Casey D, Batter S, Giovannucci E, Hennekens CH & Stampfer MJ (1999) The V89L polymorphism in the 5alpha-reductase type 2 gene and risk of prostate cancer. Cancer Res 59, 58785881.
  • 13
    Thomas LN, Lazier CB, Gupta R, Norman RW, Troyer DA, O'Brien SP & Rittmaster RS (2005) Differential alterations in 5alpha-reductase type 1 and type 2 levels during development and progression of prostate cancer. Prostate 63, 231239.
  • 14
    Thomas LN, Douglas RC, Rittmaster RS & Too CK (2009) Overexpression of 5alpha-reductase type 1 increases sensitivity of prostate cancer cells to low concentrations of testosterone. Prostate 1, 595602.
  • 15
    Sánchez P, Torres JM, Olmo A, O'Valle F & Ortega E (2009) Effects of environmental stress on mRNA and protein expression levels of steroid 5alpha-reductase isozymes in adult rat brain. Horm Behav 56, 348353.
  • 16
    Woo JM & Postolache TT (2008) The impact of work environment on mood disorders and suicide: evidence and implications. Int J Disabil Hum Dev 7, 185200.
  • 17
    Adebamowo MA (2009) Impact of environmental stress on cancer risk: a case study of an urban residential neighbourhood in Lagos metropolis. Afr J Med Med Sci 38, 4148.
  • 18
    Ellison GL, Coker AL, Hebert JR, Sanderson SM, Royal CD & Weinrich SP (2001) Psychosocial stress and prostate cancer: a theoretical model. Ethn Dis 11, 484495.
  • 19
    Coiro V, Volpi R, Galli P, Manfredi G, Magotti MG, Saccani-Jotti G & Chiodera P (2004) Serum total prostate-specific antigen assay in women with Cushing's disease or alcohol-dependent pseudo-Cushing's state. Horm Res 61, 148152.
  • 20
    Takizawa I, Hara N, Nishiyama T, Isahaya E, Hoshii T & Takahashi K (2010) Adrenocorticotropic hormone is involved in regulation of androgen synthesis in men receiving androgen deprivation therapy for localized prostate cancer. J Urol 184, 19711976.
  • 21
    Wennbo H, Kindblom J, Isaksson OGP & Tornell J (1997) Transgenic mice overexpressing the prolactin gene develop dramatic enlargement of the prostate gland. Endocrinology 138, 44104415.
  • 22
    Crépin A, Bidaux G, Vanden-Abeele F, Dewailly E, Goffin V, Prevarskaya N & Slomianny C (2007) Prolactin stimulates prostate cell proliferation by increasing endoplasmic reticulum content due to SERCA 2b over-expression. Biochem J 401, 4955.
  • 23
    Dagvadorj A, Collins S, Jomain JB, Abdulghani J, Karras J, Zellweger T, Li H, Nurmi M, Alanen K, Mirtti T et al. (2007) Autocrine prolactin promotes prostate cancer cell growth via Janus kinase-2-signal transducer and activator of transcription-5a/b signaling pathway. Endocrinology 148, 30893101.
  • 24
    Wylot M, Laszczyńska M & Chorzepa K (2006) Prolactin receptors in the prostate. Pol Merkur Lekarski 21, 492494.
  • 25
    Sánchez P, Torres JM, Castro B, Ortega J, Frías JF & Ortega E (2011) Effects of environmental stress on mRNA and protein expression levels of steroid 5alpha-reductase isozymes in prostate of adult rats. FEBS J 278, (Suppl. 1), 81.
  • 26
    Sánchez P, Torres JM, Gavete P & Ortega E (2008) Effects of swim stress on mRNA and protein levels of steroid 5alpha-reductase isozymes in prefrontal cortex of adult male rats. Neurochem Int 52, 426431.
  • 27
    Bortolato M, Devoto P, Roncada P, Frau R, Flore G, Saba P, Pistritto G, Soggiu A, Pisanu S, Zappala A et al. (2011) Isolation rearing-induced reduction of brain 5α-reductase expression: relevance to dopaminergic impairments. Neuropharmacology 60, 13011308.
  • 28
    Dong E, Matsumoto K, Uzunov V, Sugaya I, Takahata H & Nomura H (2001) Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation. Proc Natl Acad Sci USA 98, 28492854.
  • 29
    Pinna G, Dong E, Matsumoto K, Costa E & Guidotti A (2003) In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine. Proc Natl Acad Sci USA 100, 20352040.
  • 30
    Agis-Balboa RC, Pinna G, Pibiri F, Kadriu B, Costa E & Guidotti A (2007) Downregulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice. Proc Natl Acad Sci USA 104, 1873618741.
  • 31
    Pibiri F, Nelson M, Guidotti A, Costa E & Pinna G (2008) Decreased corticolimbic allopregnanolone expression during social isolation enhances contextual fear: a model relevant for posttraumatic stress disorder. Proc Natl Acad Sci USA 105, 55675572.
  • 32
    Barbaccia ML, Serra M, Purdy RH & Biggio G (2001) Stress and neuroactive steroids. Int Rev Neurobiol 46, 243272.
  • 33
    Barbaccia M, Roscetti G, Trabucchi M, Mostallino MC, Concas A, Purdy RH & Biggio G (1996) Time-dependent changes in brain neuroactive sterois concentrations and GABAA receptor function after acute stress. Neuroendocrinology 63, 166172.
  • 34
    Purdy RH, Morrow AL, Moore PH Jr & Paul SM (1991) Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain. Proc Natl Acad Sci USA 88, 45534557.
  • 35
    Torres JM, Ruiz E & Ortega E (2001) Effects of CRH and ACTH administration on plasma and brain neurosteroid levels. Neurochem Res 26, 555558.
  • 36
    Gill JK, Wilkens LR, Pollak MN, Stanczyk FZ & Kolonel LN (2010) Androgens, growth factors, and risk of prostate cancer: the Multiethnic Cohort. Prostate 1, 906915.
  • 37
    Span PN, Voller MC, Smals AG, Sweep FG, Schalken JA, Feneley MR & Kirby RS (1999) Selectivity of finasteride as an in vivo inhibitor of 5alpha-reductase isozyme enzymatic activity in the human prostate. J Urol 161, 332337.
  • 38
    Söderström T, Wadelius M, Andersson SO, Johansson JE, Johansson S, Granath F & Rane A (2002) 5alpha-reductase 2 polymorphisms as risk factors in prostate cancer. Pharmacogenetics 12, 307312.
  • 39
    Zhu YS & Imperato-McGinley JL (2009) 5alpha-reductase isozymes and androgen actions in the prostate. Ann N Y Acad Sci 1155, 4356.
  • 40
    Thompson IM, Lucia MS, Redman MW, Darke A, La Rosa FG, Parnes HL, Lippman SM & Coltman CA (2007) Finasteride decreases the risk of prostatic intraepithelial neoplasia. J Urol 178, 107110.
  • 41
    Setlur SR, Chen CX, Hossain RR, Ha JS, Van Doren VE, Stenzel B, Steiner E, Oldridge D, Kitabayashi N, Banerjee S et al. (2010) Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer. Cancer Epidemiol Biomarkers Prev 19, 229239.
  • 42
    Bayne CW, Donelly F, Ross M & Habib FK (1999) Serenoa repens (Permixon), a 5α-reductase type I and type II inhibitor: new evidence in a coculture model of BPH. Prostate 40, 232241.
  • 43
    Brawley OW, Barnes S & Parnes H (2001) The future of prostate cancer prevention. Ann NY Acad Sci 952, 145152.
  • 44
    Clark RV, Hermann DJ, Cunningham GR, Wilson TH, Morrill BB & Hobbs S (2004) Marked suppression of dihydrotestosterone in men with benign prostatic hyperplasia by dutasteride, a dual 5α-reductase inhibitor. J Clin Endocrinol Metab 89, 21792184.
  • 45
    Roehrborn CG, Nickel JC, Andriole GL, Gagnier RP, Black L, Wilson TH & Rittmaster RS (2011) Dutasteride improves outcomes of benign prostatic hyperplasia when evaluated for prostate cancer risk reduction: secondary analysis of the REduction by DUtasteride of prostate Cancer Events (REDUCE) trial. Urology 78, 641646.
  • 46
    Bauman DR, Steckelbroeck S, Peehl DM & Penning TM (2006) Transcript profiling of the androgen signal in normal prostate, benign prostatic hyperplasia, and prostate cancer. Endocrinology 147, 58065816.
  • 47
    Huynh H, Alpert L, Alaoui-Jamali MA, Ng CY & Chan TW (2001) Coadministration of finasteride and the pure antioestrogen ICI 182, 780 act synergistically in modulating the IGF system in rat prostate. J Endocrinol 17, 109118.
  • 48
    Ji Q, Chang L, VanDenBerg D, Stanczyk FZ & Stolz A (2003) Selective reduction of AKR1C2 in prostate cancer and its role in DHT metabolism. Prostate 54, 275289.
  • 49
    Mostaghel EA, Geng L, Holcomb I, Coleman IM, Lucas J, True LD & Nelson PS (2010) Variability in the androgen response of prostate epithelium to 5alpha-reductase inhibition: implications for prostate cancer chemoprevention. Cancer Res 70, 12861295.
  • 50
    Sánchez P, Torres JM, Vílchez P, Del Moral RG & Ortega E (2008) Effects of sulpiride on mRNA levels of steroid 5alpha-reductase isozymes in prostate of adult rats. IUBMB Life 60, 6872.
  • 51
    Yamanaka H, Kirdani RY, Saroff J, Murphy GP & Sandberg AA (1975) Effects of testosterone and prolactin on rat prostatic weight, 5α-reductase, and arginase. Am J Physiol 229, 11021119.
  • 52
    Steger RW, Chandrashekar V, Zhao W, Bartke A & Horseman ND (1998) Neuroendocrine and reproductive functions in male mice with targeted disruption of the prolactin gene. Endocrinology 139, 36913695.
  • 53
    Johansen C & Olsen JH (1997) Psychological stress, cancer incidence and mortality from non-malignant diseases. Br J Cancer 75, 144148.
  • 54
    Ward IL (1972) Prenatal stress feminizes and demasculinizes the behavior of males. Science 175, 8284.
  • 55
    Torres JM & Ortega E (2004) Quantitation of mRNA levels of steroid 5alpha-reductase isozymes: a novel method that combines quantitative RT-PCR and capillary electrophoresis. Int J Biochem Cell B 36, 7888.
  • 56
    Chomczynski P & Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate–phenol–chloroform extraction. Anal Biochem 162, 156159.
  • 57
    Dadras SS, Cai X, Abasolo I & Wang Z (2001) Inhibition of 5alpha-reductase in rat prostate reveals differential regulation of androgen-response gene expression by testosterone and dihydrotestosterone. Gene Expr 9, 183194.