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Table S1. Binding partners of Grb7/10/14 and SH2B adaptors.

Table S2. Functional consequences of Grb14 and insulin receptor β–subunit site-directed mutagenesis.

Table S3. Functional consequences of Grb10 and Grb14 interactions with signaling proteins downstream IR/IGFR in cultured cells.

Table S4. Phenotypes of Grb10, Grb14 and Grb10 + Grb14 knockout mice.

Table S5. Functional consequences of SH2B1 and SH2B2 site-directed mutagenesis.

Table S6. Phenotypic changes induced by SH2B1 and SH2B2 gene disruption in mice.

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